Evidence map›Paper›PMID 29809139›Full record

ArticleeLife2018

Metabolic interactions between dynamic bacterial subpopulations.

Adam Z Rosenthal, Yutao Qi, Sahand Hormoz, Jin Park, Sophia Hsin-Jung Li, Michael B Elowitz

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. MOB rules: Antibiotic Exposure Reprograms Metabolism to MobilizebioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Adam Z RosenthalDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID http://orcid.org/0000-0002-6936-3665
Yutao QiDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Sahand HormozDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Jin ParkDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Sophia Hsin-Jung LiDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID http://orcid.org/0000-0001-8972-6921
Michael B ElowitzDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID http://orcid.org/0000-0002-1221-0967

Funding

UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9M
Stochastic Pulsing in Microbial Regulation and DifferentiationR01GM079771 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ELOWITZ, MICHAEL B · 2007 to 2015
$2.8M
Lineage-based inference of cell state transition dynamics in development and diseaseR00GM118910 · NIGMS · DANA-FARBER CANCER INST · PI HORMOZ, SAHAND · 2017 to 2019
$747k
NIGMS NIH HHS R00 GM118910NIGMS NIH HHS R01 GM079771NIH HHS RO1GM079771
6 · The paper itself

Abstract

Individual microbial species are known to occupy distinct metabolic niches within multi-species communities. However, it has remained largely unclear whether metabolic specialization can similarly occur within a clonal bacterial population. More specifically, it is not clear what functions such specialization could provide and how specialization could be coordinated dynamically. Here, we show that exponentially growing

Indexed as

Gene Expression Regulation, BacterialGenes, BacterialAcetic AcidAcetoinBacillus subtilisClone CellsCulture MediaFermentationGlucoseHydrogen-Ion ConcentrationKetoglutarate Dehydrogenase ComplexMalatesMetabolic Networks and PathwaysMicrobial InteractionsTime-Lapse ImagingAcetic AcidAcetoinCulture MediaGlucoseKetoglutarate Dehydrogenase ComplexMalatesmalic acidacetateBacillus subtilisB. subtiliscomputational biologydivision of laborfermentationinfectious diseasemicrobiologyoverflow metabolismsystems biology

Identifiers

PMID29809139
PMCPMC6025961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.