Evidence map›Paper›PMID 29809136›Full record

ArticleeLife2018

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides.

Olivier Sallin, Luc Reymond, Corentin Gondrand, Fabio Raith, Birgit Koch, Kai Johnsson

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
5.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 132 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Changes in the brain [NADFrontiers in aging neuroscience · 2026
    Review
  5. Review
  6. Mitochondrial NADScience advances · 2025
    Article
  7. Optimizing multifunctional fluorescent ligands for intracellular labeling.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. A family of NADPH/NADPNature communications · 2024
    Article
  18. Review
  19. Subcellular NADNature metabolism · 2024
    Article
  20. Regulation of and challenges in targeting NADNature reviews. Molecular cell biology · 2024
    Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Olivier SallinÉcole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland.
Luc ReymondÉcole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland.
Corentin GondrandDepartment of Chemical Biology, Max-Planck-Institute for Medical Research, Heidelberg, Germany.
Fabio RaithDepartment of Chemical Biology, Max-Planck-Institute for Medical Research, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-7235-8453
Birgit KochDepartment of Chemical Biology, Max-Planck-Institute for Medical Research, Heidelberg, Germany.
Kai JohnssonÉcole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-8002-1981
Max Planck Institute for Medical Research · DEÉcole Polytechnique Fédérale de Lausanne · CHFORS – Swiss Centre of Expertise in the Social Sciences · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We introduce a new class of semisynthetic fluorescent biosensors for the quantification of free nicotinamide adenine dinucleotide (NAD

Indexed as

Biosensing TechniquesAnimalsCell Line, TumorCell NucleusCytosolFluorescence Resonance Energy TransferFluorescent DyesHEK293 CellsHeLa CellsHumansHydrogen-Ion ConcentrationKineticsMiceMitochondriaNADNADPFluorescent DyesNADNADPRecombinant Fusion ProteinsRhodaminesSulfamethoxazoleSulfapyridinetetramethylrhodaminebiochemistrybiosensorchemical biologyhumanlive-cell imagingNicotinamide adenine dinucleotides

Identifiers

PMID29809136
PMCPMC5990361
OpenAlexW2805522187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.