Evidence map›Paper›PMID 29808762›Full record

ArticleEuropean journal of preventive cardiology2018

Cardiopulmonary exercise testing reveals subclinical abnormalities in chronic kidney disease.

Danielle L Kirkman, Bryce J Muth, Joseph M Stock, Raymond R Townsend, David G Edwards

Open access · bronzeAbstract read
In one paragraph

Article in European journal of preventive cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
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  6. The Intersection of Heart Failure with Preserved Ejection Fraction and CKD.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  7. Review
  8. Article
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  11. Endothelial dysfunction in chronic kidney disease: a clinical perspective.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  12. Article
  13. Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Danielle L Kirkman1 Department of Kinesiology and Applied Physiology, University of Delaware, USA.
Bryce J Muth1 Department of Kinesiology and Applied Physiology, University of Delaware, USA.
Joseph M Stock1 Department of Kinesiology and Applied Physiology, University of Delaware, USA.
Raymond R Townsend2 Clinical and Translational Research Center, University of Pennsylvania, USA.
David G Edwards1 Department of Kinesiology and Applied Physiology, University of Delaware, USA.
University of Delaware · USTranslational Therapeutics (United States) · US

Funding

Exercise and Vascular Function in Chronic Kidney DiseaseR01HL113514 · NHLBI · UNIVERSITY OF DELAWARE · PI EDWARDS, DAVID G · 2013 to 2015
$1.2M
NHLBI NIH HHS R01 HL113514
6 · The paper itself

Abstract

Background Reductions in exercise capacity associated with exercise intolerance augment cardiovascular disease risk and predict mortality in chronic kidney disease. This study utilized cardiopulmonary exercise testing to (a) investigate mechanisms of exercise intolerance; (b) unmask subclinical abnormalities that may precede cardiovascular disease in chronic kidney disease. Design The design of this study was cross-sectional. Methods Cardiopulmonary exercise testing was carried out in 31 Stage 3-4 chronic kidney disease patients (60 ± 11 years; estimated glomerular filtration rate 43 ± 13 ml/min/1.73 m

Indexed as

Cardiorespiratory FitnessExercise TestExercise ToleranceGlomerular Filtration RateAgedAsymptomatic DiseasesBreath TestsCardiovascular DiseasesCase-Control StudiesCross-Sectional StudiesFemaleHealth StatusHeart RateHumansKidneyMaleChronic renal insufficiencyexercise test

Identifiers

PMID29808762
PMCPMC11981665
OpenAlexW2806796166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.