Evidence map›Paper›PMID 29808608›Full record

ArticleJournal of cellular and molecular medicine2018

Methylation-reprogrammed Wnt/β-catenin signalling mediated prenatal hypoxia-induced brain injury in foetal and offspring rats.

Yingying Zhang, Mengshu Zhang, Lingjun Li, Bin Wei, Axin He, Likui Lu, Xiang Li, Lubo Zhang, Zhice Xu, Miao Sun

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yingying ZhangInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Mengshu ZhangInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Lingjun LiInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Bin WeiInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Axin HeInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Likui LuInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Xiang LiInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Lubo ZhangInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Zhice XuInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.
Miao SunInstitute for Fetology, First Hospital of Soochow University, Suzhou, China.ORCID http://orcid.org/0000-0002-6414-368X
Soochow University · CNLoma Linda University · US

Funding

Developmental Programming of Ischemic-Sensitive Phenotype in the HeartR01HL118861 · NHLBI · LOMA LINDA UNIVERSITY · PI ZHANG, LUBO · 2014 to 2017
$1.8M
Jiangsu Province's Key Discipline/Laboratory of Fetal MedicineJiangsu Provincial Commission of Health and Family Planning LGY2016034Jiangsu Provincial Commission of Health and Family Planning ZDRCA2016037National Natural Science Foundation of China 81320108006National Natural Science Foundation of China 81570960NHLBI NIH HHS R01 HL118861
6 · The paper itself

Abstract

Prenatal hypoxia (PH) is a common pregnancy complication, harmful to brain development. This study investigated whether and how PH affected Wnt pathway in the brain. Pregnant rats were exposed to hypoxia (10.5% O

Indexed as

brainmethylationprenatal hypoxiaSfrp4Wnt

Identifiers

PMID29808608
PMCPMC6050486
OpenAlexW2806049436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.