SynthesisInternational wound journal2018
Haemorrhage from varicose veins and varicose ulceration: A systematic review.
Synthesis in International wound journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The 2023 Society for Vascular Surgery, American Venous Forum, and American Vein and Lymphatic Society clinical practice guidelines for the management of varicose veins of the lower extremities. Part II: Endorsed by the Society of Interventional Radiology and the Society for Vascular Medicine.Journal of vascular surgery. Venous and lymphatic disorders · 2024Guideline
- Haemorrhage from varicose veins and varicose ulceration: A systematic review.International wound journal · 2018Pooled it
- Trial
- Protocol-based treatment of spontaneous hemorrhage from varicose veins prevents recurrence of bleeding.Journal of vascular surgery. Venous and lymphatic disorders · 2025Article
- Management of bleeding varicose veins.Phlebology · 2024Article
- Risk Factors for Bleeding Varicose Veins in Patients with Chronic Venous Disease.Medicina (Kaunas, Lithuania) · 2023Article
- Brazilian guidelines on chronic venous disease of the Brazilian Society of Angiology and Vascular Surgery.Jornal vascular brasileiro · 2023Article
- Epidemiological profile of surgical treatment of varicose veins in Brazil from 2010 to 2020.Jornal vascular brasileiro · 2022Article
- Factors associated with chronic venous disease: study in 1,136 patients treated for varicose veins of the lower limbs in a specialized clinic.Jornal vascular brasileiro · 2022Article
- A rare suicide case involving fatal bleeding from varicose veins.Journal of forensic sciences · 2021Article
- Fatal hemorrhage from peripheral varicose vein rupture.Autopsy & case reports · 2021Article
- Fatal rooster attack.Forensic science, medicine, and pathology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Varicose veins (VVs) and varicose ulceration (VU) are usually considered non-life-threatening conditions, but in some cases they can lead to major complications such as fatal bleeding. The aim of this systematic review is to evidence the most updated information on bleeding from VV and VU. As evidence acquisition, we planned to include all the studies dealing with "Haemorrhage/Bleeding" and "VVs/VU". We excluded all the studies, which did not properly fit our research question, and with insufficient data. As evidence synthesis, of the 172 records found, after removing of duplicates, and after records excluded in title and abstract, 85 matched our inclusion criteria. After reading the full-text articles, we decided to exclude 68 articles because of the following reasons: (1) not responding properly to our research questions; (2) insufficient data; the final set included 17 articles. From literature searching, we identify the following main issues to be discussed in the review: epidemiology and predisposing factors, pathophysiology and forensic aspects, first aid. It has been estimated that deaths for bleeding due to peripheral venous problems account up to 0.01% of autopsy cases. From a pathological point of view, venous bleeding may arise from either acute or chronic perforation of an enlarged vein segment through the weakened skin. From a forensic point of view, in cases of fatal haemorrhage the death scene can even simulate non-natural events, due to crime or suicide. In most cases, incorrect first aid led to fatal complications. Further investigation on epidemiology and prevention measures are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.