ArticleEuropean radiology2018
Comparing dual energy CT and subtraction CT on a phantom: which one provides the best contrast in iodine maps for sub-centimetre details?
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Diagnostic value of subtraction CT in evaluating the efficacy of transcatheter arterial chemoembolization-treated hepatocellular carcinoma patients compared to conventional CT and MRI.Quantitative imaging in medicine and surgery · 2026Article
- Differentiation of Fat-Poor Renal Angiomyolipoma From Clear Cell Renal Cell Carcinoma: Diagnostic Performance of a Novel Type of Color Contrast Enhanced Ultrasound.Cancer medicine · 2026Article
- The capacity of subtraction CT iodine maps to improve the differentiation of solitary pulmonary nodules.Quantitative imaging in medicine and surgery · 2025Article
- Future Applications of Cardiothoracic CT.Radiology · 2025Review
- Feasibility Study of Triple-low CCTA for Coronary Artery Disease Screening Combining Contrast Enhancement Boost and Deep Learning Reconstruction.Reviews in cardiovascular medicine · 2025Article
- A novel method of carotid artery wall imaging: black-blood CT.European radiology · 2024Article
- Carotid artery plaque assessment using CT with iodine mapping.European radiology · 2024Article
- Area-Detector Computed Tomography for Pulmonary Functional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Contrast thresholds for detection of various iodine concentrations in subtraction CT and dual-energy CT systems.Journal of applied clinical medical physics · 2023Article
- Correlation between CT Value on Lung Subtraction CT and Radioactive Count on Perfusion Lung Single Photon Emission CT in Chronic Thromboembolic Pulmonary Hypertension.Diagnostics (Basel, Switzerland) · 2022Article
- Persistent respiratory failure after SARS-CoV-2 infection: The role of dual energy computed tomography. A case report.Radiology case reports · 2022Article
- Virtual Monochromatic Images from Dual-Energy Computed Tomography Do Not Improve the Detection of Synovitis in Hand Arthritis.Diagnostics (Basel, Switzerland) · 2022Article
- Lung aeration, ventilation, and perfusion imaging.Current opinion in critical care · 2022Review
- Subtraction iodine imaging with area detector CT to improve tumor delineation and measurability of tumor size and depth of invasion in tongue squamous cell carcinoma.Japanese journal of radiology · 2022Article
- Differentiation of renal angiomyolipoma without visible fat from small clear cell renal cell carcinoma by using specific region of interest on contrast-enhanced CT: a new combination of quantitative tools.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Diagnostic performance of dual-energy CT and subtraction CT for renal lesion detection and characterization.European radiology · 2019Article
- Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice.European radiology · 2019Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare contrast-to-noise ratios (CNRs) and iodine discrimination thresholds on iodine maps derived from dual energy CT (DECT) and subtraction CT (SCT).
methodsA contrast-detail phantom experiment was performed with 2 to 15 mm diameter tubes containing water or iodinated contrast concentrations ranging from 0.5 mg/mL to 20 mg/mL. DECT scans were acquired at 100 kVp and at 140 kVp+Sn filtration. SCT scans were acquired at 100 kVp. Iodine maps were created by material decomposition (DECT) or by subtraction of water scans from iodine scans (SCT). Matched exposure levels varied from 8 to 15 mGy. Iodine discrimination thresholds (C
resultsThe adjusted mean CNR was 1.9 times higher for SCT than for DECT. Exposure level had no effect on CNR. All observers discriminated all details ≥10 mm at 12 and 15 mGy. For sub-centimetre details, the lowest calculated C
conclusionsSCT results in higher CNR and reduced iodine discrimination thresholds compared to DECT for sub-centimetre details. KEY POINTS: • Subtraction CT iodine maps exhibit higher CNR than dual-energy iodine maps • Lower iodine concentrations can be discriminated for sub-cm details with SCT • Response times are lower using SCT compared to dual-energy CT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.