Evidence map›Paper›PMID 29808388›Full record

ReviewSeminars in immunopathology2018

Memory responses of innate lymphocytes and parallels with T cells.

Moritz Rapp, Gabriela M Wiedemann, Joseph C Sun

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in immunopathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Cutting Edge: STAT1-Mediated Epigenetic Control ofJournal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  13. Review
  14. Innate immunological memory: from plants to animals.Current opinion in immunology · 2020
    Review
  15. Review
  16. Memory and Memory-Like NK Cell Responses to Microbial Pathogens.Frontiers in cellular and infection microbiology · 2020
    Review
  17. Review
  18. Innate lymphoid cell memory.Cellular & molecular immunology · 2019
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Moritz RappRoche Pharmaceutical Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland.
Gabriela M WiedemannImmunology Program, Memorial Sloan Kettering Cancer Center, 408 East 69th Street, ZRC-1462, New York, NY, 10065, USA.
Joseph C SunImmunology Program, Memorial Sloan Kettering Cancer Center, 408 East 69th Street, ZRC-1462, New York, NY, 10065, USA. sunj@mskcc.org.ORCID 0000-0001-8062-9033
Memorial Sloan Kettering Cancer Center · USRoche (Switzerland) · CH

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The natural killer cell response against mouse cytomegalovirus infectionR01AI100874 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI Joseph Chai-Yuen Sun · 2012 to 2026
$7.4M
Regulation of Nfil3 in innate lymphocyte-mediated host immunityR01AI130043 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI SUN, JOSEPH CHAI-YUEN · 2017 to 2021
$2.8M
Natural killer cell and T-cell crosstalk in CMV infectionR56AI123658 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI HSU, KATHARINE C · 2017 to 2017
$306k
NCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI100874NIAID NIH HHS R01 AI130043NIAID NIH HHS R56 AI123658
6 · The paper itself

Abstract

Natural killer (NK) cells are classified as innate immune cells, given their ability to rapidly respond and kill transformed or virally infected cells without prior sensitization. Recently, accumulating evidence suggests that NK cells also exhibit many characteristics similar to cells of the adaptive immune system. Analogous to T cells, NK cells acquire self-tolerance during development, express antigen-specific receptors, undergo clonal-like expansion, and can become long-lived, self-renewing memory cells with potent effector function providing potent protection against reappearing pathogens. In this review, we discuss the requirements for memory NK cell generation and highlight the similarities with the formation of memory T cells.

Indexed as

Immunity, InnateImmunologic MemoryAnimalsAntigensBiomarkersCytokinesEpitopes, T-LymphocyteGene Expression RegulationHost-Pathogen InteractionsHumansKiller Cells, NaturalOrgan SpecificityPhenotypeSignal TransductionT-Lymphocyte SubsetsAntigensBiomarkersCytokinesEpitopes, T-LymphocyteImmunological memoryNatural killer cellsT cellsViral infection

Identifiers

PMID29808388
PMCPMC6054893
OpenAlexW2805154577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.