ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018
Outcome of single-trajectory rigid endoscopic third ventriculostomy and biopsy in the management algorithm of pineal region tumors: a case series and review of the literature.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Surgical management of pineal region tumors in Italy: a SINch (SINch®) National Survey with systematic review.Neurosurgical review · 2026Pooled it
- Biopsy of Pineal Tumors: Endoscopy or Stereotaxic or Neuronavigation Guided?Advances and technical standards in neurosurgery · 2026Pooled it
- The role of tumor biopsy in children with obstructive hydrocephalus treated with endoscopic third ventriculostomy: a single-center experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- The supracerebellar approach to pineal lesions: A review of history, evolution, and outcomes.Surgical neurology international · 2026Review
- Case Report: Synchronous cutaneous and pineal metastases from gastric adenocarcinoma-inter-lesion biomarker heterogeneity and multi-line targeted therapy.Frontiers in oncology · 2026Article
- Supracerebellar highway-fast and safe road to pediatric pineal tumor resection.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Understanding and Managing Pineal Parenchymal Tumors of Intermediate Differentiation: An In-Depth Exploration from Pathology to Adjuvant Therapies.Journal of clinical medicine · 2024Review
- Evolution of Surgical Management of Pineal Region Tumors in the Pediatric Population: A 17-Year Experience at a Single Institution.Pediatric neurosurgery · 2024Article
- Feasibility of extended transforaminal approach (medial subchoroid) for resection of a benign aqueductal tumor in a patient with type 1 neurofibromatosis.Neurosurgical focus: Video · 2023Article
- Single-entry two-stage rotational outside-in technique for simultaneous ventriculostomy and pineal region biopsy using traditional ventricular endoscope: technical note and comparative review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Molecular Pathology and Targeted Therapies for Personalized Management of Central Nervous System Germinoma.Journal of personalized medicine · 2021Review
- Pineal Gland Tumors: A Review.Cancers · 2021Review
- A bi-foraminal craniometric-guided approach to endoscopic third ventriculostomy and biopsy of a pineal tumour.Surgical neurology international · 2021Article
- Endoscopic resection of a low-grade ependymoma of the pineal region.Surgical neurology international · 2021Article
- Pineal region tumors: pathophysiological mechanisms of presenting symptoms.American journal of translational research · 2021Review
- Observational
- Biomarkers of Pineal Region Tumors: A Review.Ochsner journal · 2019Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTumors within the pineal region represent 1.5 to 8.5% of the pediatric brain tumors and 1.2% of all brain tumors. A management algorithm has been proposed in several publications. The algorithm includes endoscopic third ventriculostomy (ETV) and biopsy in cases presenting with hydrocephalus. In this series, we are presenting the efficacy of a single-trajectory approach for both ETV and biopsy.
methodsEleven cases were admitted to Alexandria main university hospital from 2013 to 2016 presenting with pineal region tumors and hydrocephalus. Mean age at diagnosis was 11 years (1-27 years). All cases had ETV and biopsy using rigid ventriculoscope through a single trajectory from a burr hole planned on preoperative imaging. Follow-up period was 7-48 months.
resultsAll 11 cases presented with hydrocephalus and increased intracranial pressure manifestations. Histopathological diagnosis was successful in 9 out of 11 cases (81.8%). Three cases were germ-cell tumors, two cases were pineoblastomas, two cases were pilocytic astrocytomas, and two cases were grade 2 tectal gliomas. Five of the ETV cases (45.5%) failed and required VPS later on. Other complications of ETV included one case of intraventricular hemorrhage and a case with tumor disseminated to the basal cisterns.
conclusionIn our series, we were able to achieve ETV and biopsy through a single trajectory and a rigid endoscope with results comparable to other studies in the literature.
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