Evidence map›Paper›PMID 29808290›Full record

ArticleSleep & breathing = Schlaf & Atmung2019

Sleep apnea detection: accuracy of using automated ECG analysis compared to manually scored polysomnography (apnea hypopnea index).

Hugi Hilmisson, Neale Lange, Stephen P Duntley

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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  12. Screening of obstructive sleep apnea in patients who snore using a patch-type device with electrocardiogram and 3-axis accelerometer.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hugi HilmissonMyCardio-LLC, SleepImage®, 370 Interlocken Blvd., Broomfield, CO, 80021, USA. hugi.hilmisson@sleepimage.com.
Neale LangeDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health at Denver-Anschutz Medical Campus, Denver, CO, 80045, USA.
Stephen P DuntleyCritical Care Pulmonary and Sleep Associates, 274 Union Blvd, Suite #110, Lakewood, CO, 80228, USA.
Pulmonary and Critical Care Associates · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdequate sleep is fundamental to wellness and recovery from illnesses and lack thereof is associated with disease onset and progression resulting in adverse health outcomes. Measuring sleep quality and sleep apnea (SA) at the point of care utilizing data that is already collected is feasible and cost effective, using validated methods to unlock sleep information embedded in the data. The objective of this study is to determine the utility of automated analysis of a stored, robust signal widely collected in hospital and outpatient settings, a single lead electrocardiogram (ECG), using clinically validated algorithms, cardiopulmonary coupling (CPC), to objectively and accurately identify SA.

methodsRetrospective analysis of de-identified PSG data with expert level scoring of Apnea Hypopnea Index (AHI) dividing the cohort into severe OSA (AHI > 30), moderate (AHI 15-30), mild (AHI 5-15), and no disease (AHI < 5) was compared with automated CPC analysis of a single lead ECG collected during sleep for each subject. Statistical analysis was used to compare the two methods.

resultsSixty-eight ECG recordings were analyzed. CPC identified patients with moderate to severe SA with sensitivity of 100%, specificity of 81%, and agreement of 93%, LR+ (positive likelihood ratio) 5.20, LR- (negative likelihood ratio) 0.00 and kappa 0.85 compared with manual scoring of AHI.

conclusionThe automated CPC analysis of stored single lead ECG data often collected during sleep in the clinical setting can accurately identify sleep apnea, providing medically actionable information that can aid clinical decisions.

Indexed as

AdultAgedAlgorithmsElectrocardiographyFemaleHumansMaleMiddle AgedPolysomnographyRetrospective StudiesSensitivity and SpecificitySleep Apnea, ObstructiveSleep StagesApnea Hypopnea IndexCardiopulmonary couplingCyclic variation of heart rateSleep apnea

Identifiers

PMID29808290
OpenAlexW2807403849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.