Evidence map›Paper›PMID 29808168›Full record

ArticleBioMed research international2018

Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis.

Linda Ahenkorah Fondjo, Samuel Asamoah Sakyi, William K B A Owiredu, Edwin Ferguson Laing, Eddie-Williams Owiredu, Ebenezer Kwesi Awusi, Richard K D Ephraim, Osei Sarfo Kantanka

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  8. Review
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  11. Observational
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  13. Association of Hypovitaminosis D with Metabolic Syndrome in Postmenopausal Women.Journal of obstetrics and gynaecology of India · 2020
    Review
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  16. Review
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  19. Article
  20. Impact of Vitamin D status on age at menopause: A prospective cohort study.Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Linda Ahenkorah FondjoDepartment of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0003-0252-3190
Samuel Asamoah SakyiDepartment of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0001-5168-4762
William K B A OwireduDepartment of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0002-8920-1284
Edwin Ferguson LaingDepartment of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Eddie-Williams OwireduDepartment of Medical Laboratory Technology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ebenezer Kwesi AwusiDepartment of Medical Laboratory Technology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Richard K D EphraimDepartment of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0001-5572-9059
Osei Sarfo KantankaDepartment of Medicine, Diabetic Clinic, Komfo Anokye Teaching Hospital, Kumasi, Ghana.ORCID 0000-0002-4451-5749
Kwame Nkrumah University of Science and Technology · GHKomfo Anokye Teaching Hospital · GHUniversity of Cape Coast · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 Diabetes Mellitus (T2DM) and menopause are associated with vitamin D status. Oestrogen decline during menopausal stages promotes hypovitaminosis D. However, the interplay between vitamin D, menopause, lifestyle, and T2DM cannot be overlooked. This study assessed vitamin D status among pre- and postmenopausal T2DM women and determined its association with glycemic control and influence of lifestyle habits on hypovitaminosis D.

methodsThis cross-sectional study was conducted at the Komfo Anokye Teaching Hospital, Kumasi, Ghana. Structured questionnaires were administered to 192 T2DM women; blood samples were collected for estimation of 25(OH) D and insulin using ELISA. Fasting blood glucose (FBG), lipid profile, glycated haemoglobin (HbA1c), and calcium were measured. Statistical analyses were performed using Graphpad Prism 6.

resultsThe prevalence of vitamin D inadequacy was 92.2%. Hypovitaminosis D was more prevalent among the postmenopausal T2DM women (63.8% versus 58.2%). Hypovitaminosis D significantly associated with insulin [

conclusionVitamin D deficiency is prevalent in pre- and postmenopausal T2DM but higher among postmenopausal women. Adequate vitamin D levels in both groups were associated with improved glucose control while hypovitaminosis D in the postmenopausal women was related to poorer glucose control. Vitamin D screening should be incorporated into management plan for T2DM to serve as an early tool for prevention of vitamin D deficiency.

Indexed as

Blood PressureBody Mass IndexCross-Sectional StudiesDiabetes Mellitus, Type 2GhanaHumansLipidsPostmenopauseVitamin DVitamin D DeficiencyLipidsVitamin D

Identifiers

PMID29808168
PMCPMC5902073
OpenAlexW2796045767

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.