Evidence map›Paper›PMID 29808163›Full record

ArticleBioMed research international2018

Luteinizing Hormone/Human Chorionic Gonadotropin Receptor Immunohistochemical Score Associated with Poor Prognosis in Endometrial Cancer Patients.

Flavia Sorbi, Elisabetta Projetto, Irene Turrini, Gianna Baroni, Serena Pillozzi, Viola Ghizzoni, Federica Vergoni, Francesca Castiglione, Francesca Malentacchi, Massimiliano Fambrini and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Flavia SorbiDepartment of Biomedical Clinical and Experimental Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.ORCID 0000-0001-7277-6420
Elisabetta ProjettoDivision of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Irene TurriniDepartment of Biomedical Clinical and Experimental Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Gianna BaroniDivision of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Serena PillozziDepartment of Experimental and Clinical Medicine, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Viola GhizzoniDepartment of Biomedical Clinical and Experimental Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Federica VergoniDivision of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Francesca CastiglioneDivision of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Francesca MalentacchiDepartment of Biomedical Clinical and Experimental Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Massimiliano FambriniDepartment of Biomedical Clinical and Experimental Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Ivo NociDepartment of Biomedical Clinical and Experimental Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to develop a scoring system of the immunohistochemical (IHC) expression of luteinizing hormone/human chorionic gonadotropin receptor (LHCG-R) in endometrial cancer (EC) patients. Nonconsecutive hysterectomy specimens containing EC collected from April 2013 to October 2015 were selected. Hematoxylin-eosin stained sections from each case were reviewed and representative sections from each tumor were selected. IHC staining was performed for the detection of LHCG-R. The percentage of stained cells and the staining intensity were assessed in order to develop an immunohistochemical score. Moreover, we examined the correlation of the score with grading and lymphovascular space invasion (LVSI). There was a statistically significant positive correlation between grading and IHC scoring (

Indexed as

AdultAgedAged, 80 and overCohort StudiesEndometrial NeoplasmsFemaleHumansImmunohistochemistryMiddle AgedPrognosisReceptors, LHReceptors, LH

Identifiers

PMID29808163
PMCPMC5902075
OpenAlexW2795569042

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.