Evidence map›Paper›PMID 29808030›Full record

ArticleNature genetics2018

The fecal metabolome as a functional readout of the gut microbiome.

Jonas Zierer, Matthew A Jackson, Gabi Kastenmüller, Massimo Mangino, Tao Long, Amalio Telenti, Robert P Mohney, Kerrin S Small, Jordana T Bell, Claire J Steves and 3 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Nature genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05990166 (Randomised Controlled Trial to Assess the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age), which is not on this map. Cited by 431 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
431citing papers in PubMed, 4 pooled it
29.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05990166 phase2completednot on this mapstarted 2023, after this paper: background citation

Randomised Controlled Trial to Assess the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age

TypeinterventionalSponsorCarleton UniversityRan2023 to 2026Enrolled150ConditionsIron Deficiency, Iron Deficiency AnaemiaArmsMineral-enriched powder, Placebo powder
3 · Its place in the literature

Who cites it

431 citing papers in PubMed, 4 syntheses or guidelines pooled it, 723 citations in OpenAlex.

  1. Pooled it
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  5. Nutrients · 2026
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371 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Jonas ZiererDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.ORCID http://orcid.org/0000-0002-9693-1859
Matthew A JacksonDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.ORCID http://orcid.org/0000-0002-7891-6217
Gabi KastenmüllerInstitute of Bioinformatics and Systems Biology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Massimo ManginoDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.ORCID http://orcid.org/0000-0002-2167-7470
Tao LongHuman Longevity, Inc, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-7052-9546
Amalio TelentiHuman Longevity, Inc, San Diego, CA, USA.
Robert P MohneyMetabolon, Inc, Durham, NC, USA.ORCID http://orcid.org/0000-0002-9315-9541
Kerrin S SmallDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.ORCID http://orcid.org/0000-0003-4566-0005
Jordana T BellDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.
Claire J StevesDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.
Ana M ValdesDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK.
Tim D SpectorDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK. tim.spector@kcl.ac.uk.
Cristina MenniDepartment for Twin Research & Genetic Epidemiology, King's College London, London, UK. cristina.menni@kcl.ac.uk.ORCID http://orcid.org/0000-0001-9790-0571
King's College London · GBHelmholtz Zentrum München · DEHuman Longevity (United States) · USMetabolon (United States) · USSanford Burnham Prebys Medical Discovery Institute · USUniversity of Nottingham · GB

Funding

Medical Research Council MR/M016560/1Medical Research Council MR/N01183X/1Medical Research Council MR/N030125/1Wellcome Trust
6 · The paper itself

Abstract

The human gut microbiome plays a key role in human health

Indexed as

Gastrointestinal MicrobiomeAgedArylamine N-AcetyltransferaseFecesFemaleGastrointestinal TractHumansMaleMetabolomeObesityRNA, Ribosomal, 16SArylamine N-AcetyltransferaseRNA, Ribosomal, 16S

Identifiers

PMID29808030
PMCPMC6104805
OpenAlexW2804621837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.