Evidence map›Paper›PMID 29808013›Full record

ArticleBritish journal of cancer2018

Proximity to overhead power lines and childhood leukaemia: an international pooled analysis.

Aryana T Amoon, Catherine M Crespi, Anders Ahlbom, Megha Bhatnagar, Isabelle Bray, Kathryn J Bunch, Jacqueline Clavel, Maria Feychting, Denis Hémon, Christoffer Johansen and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Aryana T AmoonDepartment of Epidemiology, University of California Los Angeles Fielding School of Public Health, Los Angeles, CA, 90095-1772, USA.
Catherine M CrespiDepartment of Biostatistics, University of California Los Angeles Fielding School of Public Health, Los Angeles, CA, 90095-1772, USA.
Anders AhlbomUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Megha BhatnagarDepartment of Epidemiology, University of California Los Angeles Fielding School of Public Health, Los Angeles, CA, 90095-1772, USA.
Isabelle BrayDepartment of Health and Social Sciences, University of the West of England, Bristol, BS16 1QY, UK.
Kathryn J BunchNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Headington, Oxford, OX3 7LF, UK.
Jacqueline ClavelEpidemiology of Childhood and Adolescent Cancers, CRESS, INSERM, UMR 1153, Paris Descartes University, Villejuif, France.
Maria FeychtingUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Denis HémonEpidemiology of Childhood and Adolescent Cancers, CRESS, INSERM, UMR 1153, Paris Descartes University, Villejuif, France.
Christoffer JohansenThe Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark.
Christian KreisInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Carlotta MalagoliResearch Center of Environmental (CREAGEN), Genetic and Nutritional Epidemiology University of Modena and Reggio Emilia, Modena, Italy.
Fabienne MarquantEpidemiology of Childhood and Adolescent Cancers, CRESS, INSERM, UMR 1153, Paris Descartes University, Villejuif, France.
Camilla PedersenThe Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark.
Ole Raaschou-NielsenThe Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark.
Martin RöösliDepartment of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Ben D SpycherInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Madhuri SudanDepartment of Epidemiology, University of California Los Angeles Fielding School of Public Health, Los Angeles, CA, 90095-1772, USA.
John SwansonNational Grid, London, UK.
Andrea TittarelliCancer Registry Unit, National Cancer Institute, Milan, 20133, Italy.
Deirdre M TuckSchool of Medicine, University of Tasmania, Hobart, TAS, Australia.
Tore TynesDepartment of Occupational Health Surveillance, National Institute of Occupational Health, Oslo, Norway.
Ximena VergaraDepartment of Epidemiology, University of California Los Angeles Fielding School of Public Health, Los Angeles, CA, 90095-1772, USA.
Marco VincetiResearch Center of Environmental (CREAGEN), Genetic and Nutritional Epidemiology University of Modena and Reggio Emilia, Modena, Italy.
Victor Wünsch-FilhoDepartment of Epidemiology, School of Public Health, University of São Paulo, São Paulo, 01246-904, Brazil.
Leeka KheifetsDepartment of Epidemiology, University of California Los Angeles Fielding School of Public Health, Los Angeles, CA, 90095-1772, USA. kheifets@ucla.edu.

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
NCI NIH HHS P30 CA016042
6 · The paper itself

Abstract

backgroundAlthough studies have consistently found an association between childhood leukaemia risk and magnetic fields, the associations between childhood leukaemia and distance to overhead power lines have been inconsistent. We pooled data from multiple studies to assess the association with distance and evaluate whether it is due to magnetic fields or other factors associated with distance from lines.

methodsWe present a pooled analysis combining individual-level data (29,049 cases and 68,231 controls) from 11 record-based studies.

resultsThere was no material association between childhood leukaemia and distance to nearest overhead power line of any voltage. Among children living < 50 m from 200 + kV power lines, the adjusted odds ratio for childhood leukaemia was 1.33 (95% CI: 0.92-1.93). The odds ratio was higher among children diagnosed before age 5 years. There was no association with calculated magnetic fields. Odds ratios remained unchanged with adjustment for potential confounders.

conclusionsIn this first comprehensive pooled analysis of childhood leukaemia and distance to power lines, we found a small and imprecise risk for residences < 50 m of 200 + kV lines that was not explained by high magnetic fields. Reasons for the increased risk, found in this and many other studies, remains to be elucidated.

Indexed as

AdolescentChildChild, PreschoolElectric Power SuppliesEnvironmental ExposureFemaleHumansInfantInfant, NewbornLeukemiaMagnetic FieldsMaleResidence CharacteristicsRisk Factors

Identifiers

PMID29808013
PMCPMC6068168

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.