Evidence map›Paper›PMID 29807713›Full record

ReviewTrends in cell biology2018

Skin Cell Heterogeneity in Development, Wound Healing, and Cancer.

Emanuel Rognoni, Fiona M Watt

Open access · hybridAbstract readReview
In one paragraph

Review in Trends in cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 2 pooled it
33.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 2 syntheses or guidelines pooled it, 282 citations in OpenAlex.

  1. Pooled it
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  8. Citrus limon-Derived Extracellular Vesicles Promote Hair Growth.Applied biochemistry and biotechnology · 2026
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97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Emanuel RognoniKing's College London, Centre for Stem Cells and Regenerative Medicine, 28th Floor, Tower Wing, Guy's Hospital Campus, Great Maze Pond, London SE1 9RT, UK.
Fiona M WattKing's College London, Centre for Stem Cells and Regenerative Medicine, 28th Floor, Tower Wing, Guy's Hospital Campus, Great Maze Pond, London SE1 9RT, UK. Electronic address: fiona.watt@kcl.ac.uk.
Guy's Hospital · GBKing's College London · GB

Funding

Cancer Research UK C219/A23522Department of Health IS-BRC-1215-20006Medical Research Council G1100073Medical Research Council MR/P018823/1Medical Research Council MR/PO18823/1Wellcome TrustWellcome Trust 206439/Z/17/Z
6 · The paper itself

Abstract

Skin architecture and function depend on diverse populations of epidermal cells and dermal fibroblasts. Reciprocal communication between the epidermis and dermis plays a key role in skin development, homeostasis and repair. While several stem cell populations have been identified in the epidermis with distinct locations and functions, it is now recognised that there is additional heterogeneity within the mesenchymal cells of the dermis. Here, we discuss recent insights into how these distinct cell populations are maintained and coordinated during development, homeostasis, and wound healing. We highlight the importance of the local environment, or niche, in cellular plasticity. We also discuss new mechanisms that have been identified as influencing wound repair and cancer progression.

Indexed as

Wound HealingAnimalsEpithelial CellsFibrosisHumansNeoplasmsSkinStem Cellsfibroblast lineagesmicronichesskin cancerstem cell plasticitywound healing

Identifiers

PMID29807713
PMCPMC6098245
OpenAlexW2804328359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.