Evidence map›Paper›PMID 29807648›Full record

ArticleSurgery2018

Risk-stratified clinical pathways decrease the duration of hospitalization and costs of perioperative care after pancreatectomy.

Jason W Denbo, Morgan Bruno, Whitney Dewhurst, Michael P Kim, Ching-Wei Tzeng, Thomas A Aloia, Jose Soliz, Barbara Bryce Speer, Jeffrey E Lee, Matthew H G Katz

Open access · greenAbstract read
In one paragraph

Article in Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Short-Term Outcomes and Cost of Robotic Versus Open Distal Pancreatectomy During the Initial Phase of a Robotic Pancreatectomy Program.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
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  12. Review
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  14. Evaluation and Recalibration of Risk-Stratified Pancreatoduodenectomy Drain Fluid Amylase Removal Criteria.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  15. Postoperative Opioid Use Is Associated with Increased Rates of Grade B/C Pancreatic Fistula After Distal Pancreatectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
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  16. Article
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  18. Incidence of Postoperative Complications Following Pancreatectomy for Pancreatic Cystic Lesions or Pancreatic Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jason W DenboDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX; Department of Surgery, University of Minnesota, Minneapolis, MN.
Morgan BrunoDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Whitney DewhurstDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Michael P KimDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Ching-Wei TzengDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Thomas A AloiaDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Jose SolizDepartment of Anesthesia, University of Texas MD Anderson Cancer Center, Houston, TX.
Barbara Bryce SpeerDepartment of Anesthesia, University of Texas MD Anderson Cancer Center, Houston, TX.
Jeffrey E LeeDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Matthew H G KatzDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address: mhgkatz@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USUniversity of Minnesota · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

backgroundPostoperative pancreatic fistula is associated with adverse events, increased duration of stay and hospital costs. We developed perioperative care pathways stratified by postoperative pancreatic fistula risk with the aims of minimizing variations in care, improving quality, and decreasing costs. STUDY

designThree unique risk-stratified pancreatectomy clinical pathways-low-risk pancreatoduodenectomy, high-risk pancreatoduodenectomy, and distal pancreatectomy were developed and implemented. Consecutive patients treated after implementation of the risk-stratified pancreatectomy clinical pathways were compared with patients treated immediately prior. Duration of stay, rates of perioperative adverse effects, discharge disposition, and hospital readmission, as well as the associated costs of care, were evaluated.

resultsThe median hospital stay after pancreatectomy decreased from 10 to 6 days after implementation of the risk-stratified pancreatectomy clinical pathways (P < .001), and the median cost of index hospitalization decreased by 22%. Decreased changes in median hospital stay and costs of hospitalization were observed in association with low-risk pancreatoduodenectomy (P < .05) and distal pancreatectomy (P < .05), but not high-risk pancreatoduodenectomy. The rates of 90-day adverse events, grade B/C postoperative pancreatic fistula, discharge to a facility other than home, or readmission did not change after implementation.

conclusionImplementation of risk-stratified pancreatectomy clinical pathways decreased median stay and cost of index hospitalization after pancreatectomy without unfavorably affecting rates of perioperative adverse events or readmission, or discharge disposition. Outcomes were most favorably improved for low-risk pancreatoduodenectomy and distal pancreatectomy. Additional work is necessary to decrease the rate of postoperative pancreatic fistula, minimize variability, and improve outcomes after high-risk pancreatoduodenectomy.

Indexed as

Critical PathwaysHealth Care CostsPancreatectomyPancreaticoduodenectomyAgedFemaleHospitalizationHumansMaleMiddle AgedPancreatic DiseasesPancreatic FistulaPerioperative CarePostoperative ComplicationsRetrospective StudiesRisk Assessment

Identifiers

PMID29807648
PMCPMC7265789
OpenAlexW2803103791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.