ArticlePsychological medicine2019
The association between depressive and sleep symptoms for predicting incident disease onset after 6-year follow-up: findings from the English Longitudinal Study of Ageing.
Article in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Personality and Risk of Arthritis in Six Longitudinal Samples.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Pooled it
- The triangulation of multimorbidity: A systematic review of primary sleep disorders, hypertension, and psychiatric disorders.PLOS global public health · 2025Article
- Treatment Modalities for Insomnia in Adults Aged 55 and Older: A Systematic Review of Literature from 2018 to 2023.Current sleep medicine reports · 2024Article
- Associations of emotional social support, depressive symptoms, chronic stress, and anxiety with hard cardiovascular disease events in the United States: the multi-ethnic study of atherosclerosis (MESA).BMC cardiovascular disorders · 2023Article
- Sex differences in residual somatic symptoms in patients with first-episode depression after acute-phase treatment.BMC psychiatry · 2023Article
- Prevalence and associated factors of cross-sectional and incident self-reported arthritis or rheumatism among a national community sample of middle-aged and older adults in Thailand.Frontiers in public health · 2023Article
- Association of Depression and Anxiety With the Accumulation of Chronic Conditions.JAMA network open · 2022Article
- Experience of depression in older adults with and without a physical long-term condition: findings from a qualitative interview study.BMJ open · 2022Article
- Longitudinal Changes in Depressive Symptoms and Risks of Cardiovascular Disease and All-Cause Mortality: A Nationwide Population-Based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Association between muscle strength and depressive symptoms among Chinese female college freshmen: a cross-sectional study.BMC musculoskeletal disorders · 2020Article
- Association of Depressive Symptoms With Incident Cardiovascular Diseases in Middle-Aged and Older Chinese Adults.JAMA network open · 2019Article
- Depressive symptoms and sleep problems as risk factors for heart disease: a prospective community study.Epidemiology and psychiatric sciences · 2019Article
- The heart of the matter: in search of causal effects of depression on somatic diseases.BMC medicine · 2018Article
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2 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe independent effects of depressive symptoms and sleep problems for future physical illness risk have yet to be studied systematically across a variety of disease endpoints.
methodsWe analysed data from 7395 participants (65.81 ± 9.39 years; 54.8% female) from the English Longitudinal Study of Ageing (ELSA). Baseline was wave 4 and participants were followed up for 6 years until wave 7. Sleep was measured using an adapted version of the Jenkins Sleep Problems questionnaire and depressive symptoms using the Centre for Epidemiological Studies Depression scale. Participants with the illness of interest at baseline [coronary heart disease (CHD), cancer, diabetes/high blood glucose, arthritis] were excluded from models predicting the onset of that illness at follow-up. Logistic regression was used, entering depressive symptoms and sleep problems simultaneously into models controlling for a wide range of covariates.
resultsIn fully adjusted models depressive symptoms predicted incident CHD (OR 1.11, 95% CI 1.04-1.20, p = 0.004) and diabetes/high blood glucose (OR 1.13, 95% CI 1.04-1.22, p = 0.002) independent of sleep problems; both depressive symptoms (OR 1.10, 95% CI 1.04-1.16, p = 0.002) and sleep problems (OR 1.14, 95% CI 1.02-1.26, p = 0.019) predicted incident arthritis.
conclusionsSleep problems and depressive symptoms, and a combination of both, were differentially associated with physical illness onset 6 years later. Our findings highlight the importance of taking into account somatic and affective experiences when looking across a variety of different physical illnesses.
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