Evidence map›Paper›PMID 29806133›Full record

ArticleAnimal science journal = Nihon chikusan Gakkaiho2018

Probiotic supplementation improves reproductive performance of unvaccinated farmed sows infected with porcine epidemic diarrhea virus.

Takamitsu Tsukahara, Takio Inatomi, Konosuke Otomaru, Masaaki Amatatsu, Gustavo A Romero-Pérez, Ryo Inoue

Abstract read
In one paragraph

Article in Animal science journal = Nihon chikusan Gakkaiho, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Synergistic effects ofVeterinary world · 2025
    Article
  3. Article
  4. MaternalComputational and structural biotechnology journal · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Detection of EnterotoxigenicLife (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Frontiers in microbiology · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takamitsu TsukaharaKyoto Institute of Nutrition & Pathology, Kyoto, Japan.ORCID http://orcid.org/0000-0002-3902-5956
Takio InatomiInatomi Animal Hospital, Tokyo, Japan.
Konosuke OtomaruJoint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Masaaki AmatatsuTOA Pharmaceutical Co. Ltd., Tokyo, Japan.
Gustavo A Romero-PérezKyoto Institute of Nutrition & Pathology, Kyoto, Japan.
Ryo InoueLaboratory of Animal Science, Kyoto Prefectural University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-7233-366X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated if probiotic supplementation could improve the health and reproductive performance of unvaccinated lactating sows infected with porcine epidemic diarrhea (PED) virus. Twenty unvaccinated pregnant sows were equally allocated to probiotic-supplemented (P) and control (C) groups. For the experiment, 15 g/day of probiotic compound BIO-THREE PZ was given to P sows. Reproductive performance was checked daily. The number of neonates fostered by each sow was maintained at eight throughout the experiment. Individual milk production post-parturition was measured twice. Milk protein and fat ratios were determined by a milk analyzer. Total immunoglobulin (Ig) A and G concentrations were measured by ELISA. At day 7 post-parturition, the body weight of P sows was 10 kg higher than that of C sows, and at day 3 post-parturition, P sows produced more milk (+2 kg) and had a higher IgA concentration in whey than did C sows (p < .05). Finally, unlike C sows, P sows tended to return to estrus faster, and had larger piglets at birth with a lower mortality percentage during early days of suckling. In conclusion, probiotic compound BIO-THREE PZ helped strengthen the immune system of unvaccinated, PED-infected sows and improved their reproductive performance.

Indexed as

Dietary SupplementsAnimalsDiarrheaDietEstrusFemaleImmunoglobulin AImmunoglobulin GLactationMilkMilk ProteinsPregnancyProbioticsReproductionSwineImmunoglobulin AImmunoglobulin GMilk Proteinsmilk productionporcine epidemic diarrheaprobiotic compoundreproductive performancesow

Identifiers

PMID29806133
PMCPMC7159621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.