Evidence map›Paper›PMID 29806118›Full record

ArticleTransboundary and emerging diseases2018

Molecular detection, isolation and characterization of Peste-des-petits ruminants virus from goat milk from outbreaks in Bangladesh and its implication for eradication strategy.

Brian Donald Clarke, Mohammad Rafiqul Islam, Mohammad Abu Yusuf, Mana Mahapatra, Satya Parida

Open access · hybridAbstract read
In one paragraph

Article in Transboundary and emerging diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  11. Peste des Petits Ruminants Virus Exhibits Cell-Dependent Interferon Active Response.Frontiers in cellular and infection microbiology · 2022
    Article
  12. Article
  13. Review of Peste des Petits Ruminants Occurrence and Spread in Tanzania.Animals : an open access journal from MDPI · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Brian Donald ClarkeThe Pirbright Institute, Woking, UK.
Mohammad Rafiqul IslamBangladesh Agricultural Research Council, Farmgate, Bangladesh.
Mohammad Abu YusufSAARC Regional Leading Diagnostic Laboratory for PPR, Bangladesh Livestock Research Institute, Savar, Bangladesh.
Mana MahapatraThe Pirbright Institute, Woking, UK.
Satya ParidaThe Pirbright Institute, Woking, UK.ORCID http://orcid.org/0000-0001-8253-9461
The Pirbright Institute · GBBangladesh Livestock Research Institute · BDBangladesh Medical Research Council · BD

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007031Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007036Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Biotechnology and Biological Sciences Research Council (BBSRC) BB/L013657/1DBT-BBSRC FADH BB/L004801/1The Pirbright Institute Strategic Programme Grants BBS/E/I/00007031The Pirbright Institute Strategic Programme Grants BBS/E/I/00007034-37
6 · The paper itself

Abstract

Peste-des-petits ruminants (PPR) is a highly contagious transboundary viral disease of small ruminants, which is endemic in much of Africa, the Middle East and Asia. In South Asia, PPR is of significant concern to the Indian subcontinent including Bangladesh as more than 30% of the world's sheep and goats are farmed in this region, predominantly by small, poor and marginal farmers. PPR virus was detected and isolated from goat milk from field samples from PPR outbreaks (2012-2015) in Bangladesh and its full-length sequences obtained. Sequence analysis of the partial N gene of Bangladesh isolates showed 99.3%-100% identity whereas 98.2%-99.6% identity was observed when compared with neighbouring Indian viruses. Further analysis of the full-length genomes indicated that the Bangladesh isolates were 99.3%-99.99% identical among themselves and 98.3%-98.4% identical to neighbouring Indian viruses. These findings further support the transboundary transmission of PPR virus across the Indian and Bangladesh border. In additional, the establishment of a cross-border strategy between India and Bangladesh will be of paramount importance for the eradication of PPR in this region. Molecular detection and isolation of PPR virus from milk is of significant potential concern for spread of the disease to free areas as the major producers of goat milk globally are PPR endemic countries in particular India and Bangladesh, as well as Sudan. Milk is a noninvasive sample type and bulk goat milk sampling for the detection of PPRV would be of practical significance for regional surveillance of PPRV as progress is made towards the targeted 2030 eradication.

Indexed as

GoatsAnimalsBangladeshDisease OutbreaksFecesGenome, ViralGoat DiseasesIndiaMilkPeste-des-Petits-RuminantsPeste-des-petits-ruminants virusReal-Time Polymerase Chain ReactionRNA, ViralRNA, Viralgoatslineage IV PPRVmorbillivirusnoninvasive samplephylogenetic analysisPPRPPR virus in milk

Identifiers

PMID29806118
PMCPMC6282541
OpenAlexW2806646649

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.