Evidence map›Paper›PMID 29806000›Full record

ArticleACS central science2018

Polymerization-Induced Self-Assembly of Micelles Observed by Liquid Cell Transmission Electron Microscopy.

Mollie A Touve, C Adrian Figg, Daniel B Wright, Chiwoo Park, Joshua Cantlon, Brent S Sumerlin, Nathan C Gianneschi

Abstract read
In one paragraph

Article in ACS central science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Polymerization-Induced Self-Assembly of Nonlinear Polymers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Liquid Phase TEM of Diffusing Emulsion Droplets.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Reverse Sequence Polymerization-Induced Self-Assembly in Aqueous Media.Angewandte Chemie (International ed. in English) · 2022
    Article
  10. Review
  11. Article
  12. ACS omega · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mollie A TouveDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, United States.
C Adrian FiggGeorge & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Daniel B WrightDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, United States.
Chiwoo ParkDepartment of Industrial & Manufacturing Engineering, Florida State University, Tallahassee, Florida 32310, United States.
Joshua CantlonSCIENION AG, Berlin 12489, Germany.
Brent S SumerlinGeorge & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Nathan C GianneschiDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we describe the use of liquid cell transmission electron microscopy (LCTEM) for inducing and imaging the formation of spherical micelles from amphiphilic block copolymers. Within the irradiated region of the liquid cell, diblock copolymers were produced which self-assembled, yielding a targeted spherical micellar phase via polymerization-induced self-assembly (PISA). Critically, we demonstrate that nanoparticle formation can be visualized in situ and that in the presence of excess monomer, nanoparticle growth occurs to yield sizes and morphologies consistent with standard PISA conditions. Experiments were enabled by employing automated LCTEM sample preparation and by analyzing LCTEM data with multi-object tracking algorithms designed for the detection of low-contrast materials.

Identifiers

PMID29806000
PMCPMC5968509

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.