ReviewJournal of immunology research2018
Salivary Gland Pathology in IgG4-Related Disease: A Comprehensive Review.
Review in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- A Mouthful of Genomic Data: Single-Cell Insights into Salivary Gland Biology and Disease.Biology · 2026Review
- An Ultrasound-Based Machine Learning Model for Differentiating IgG4-Related Sialadenitis and Primary Sjögren's Syndrome.International dental journal · 2026Article
- Surgical management of recurrent spinal hypertrophic pachymeningitis: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- How Can Radiological Limitations in Atypical Clinical Submandibular Gland Küttner Tumor (IgG-4 Disease) Mimic an Atypical Occurrence of a Solid Salivary Gland Tumor?Diagnostics (Basel, Switzerland) · 2025Article
- Clinicopathological Pearls and Diagnostic Pitfalls in IgG4-Related Disease: Challenging Case Series and Literature Review.Diagnostics (Basel, Switzerland) · 2025Article
- IgG4-related Disease Manifesting as Autoimmune Pancreatitis, Sialadenitis, and Cholangitis: Case Report.Acta medica Lituanica · 2025Article
- [Immunoglobulin G4 disease with pancreatic affectation: the mimicker of malignancy].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Activation of fibroblasts by plasma cells via PDGF/PDGFR signaling in IgG4-related sialadenitis.Journal of clinical and experimental hematopathology : JCEH · 2024Article
- Current developments and opportunities of pluripotent stem cells-based therapies for salivary gland hypofunction.Frontiers in cell and developmental biology · 2024Review
- Hyperosmolar environment and salivary gland epithelial cells increase extra-cellular matrix remodeling and lymphocytic infiltration in Sjögren's syndrome.Clinical and experimental immunology · 2023Article
- Article
- IgG4-RD in a Unilateral Parotid Mass: A Rare Manifestation and Review of the Literature.Cureus · 2023Article
- Survival in Patients with Primary Parotid Gland Carcinoma after Surgery-Results of a Single-Centre Study.Current oncology (Toronto, Ont.) · 2023Article
- Cytotoxic CD8Scientific reports · 2022Article
- Pseudocontinuous Arterial Spin Labeling: Clinical Applications and Usefulness in Head and Neck Entities.Cancers · 2022Review
- Immunohistochemical analysis of pyroptosis-related protein expression in IgG4-related sialadenitis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2022Article
- T Cell Roles and Activity in Chronic Sclerosing Sialadenitis as IgG4-Related Disease: Current Concepts in Immunopathogenesis.Autoimmune diseases · 2022Review
- Routine IgG4 staining in minor salivary gland biopsy in a cohort of Italian Caucasian patients suffering from xerostomia.Reumatologia · 2022Article
- Ocular manifestation in a patient with IgG4 related disease.Caspian journal of internal medicine · 2022Article
- Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis.Arthritis research & therapy · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgG4-related disease (IgG4-RD) is a rare fibroinflammatory condition that can affect almost any organ, characterized by swollen lesions and often by eosinophilia and elevated serum IgG4 concentrations. The diagnosis of IgG4-RD is a challenging task: in fact, single or multiple organs can be affected and clinical, serological, and histological findings can be heterogeneous. In IgG4-RD, the involvement of salivary glands is observed in 27% to 53% of patients. Several organ-specific conditions, now recognized as different manifestations of IgG4-related sialadenitis (IgG4-RS), were viewed in the past as individual disease entities. The study of salivary glands may sometimes be complex, because of the number of pathological conditions that may affect them, often with overlapping clinical pictures. Integration of different imaging techniques is often required in the case of swelling of salivary glands, even though biopsy remains the gold standard for a definite diagnosis of IgG4-RS. Thus, in this review, we discuss new insights in the pathogenesis of IgG4-RD, focusing on its clinical aspects and the tools that are currently available for a correct differential diagnosis when the salivary glands are involved.
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