Evidence map›Paper›PMID 29805971›Full record

ArticleInternational journal of chronic diseases2018

Reduction of Liver Span and Parameters of Inflammation in Nonalcoholic Fatty Liver Disease Patients Treated with Lycosome Formulation of Phosphatidylcholine: A Preliminary Report.

Ivan M Petyaev, Pavel Y Dovgalevsky, Natalia E Chalyk, Victor A Klochkov, Nigel H Kyle, Yuriy K Bashmakov

Open access · hybridAbstract read
In one paragraph

Article in International journal of chronic diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ivan M PetyaevLycotec Ltd, Granta Park Campus, Cambridge CB21 6GP, UK.ORCID 0000-0001-8201-6863
Pavel Y DovgalevskyInstitute of Cardiology, Saratov State Medical University, 12 Chernyshevskogo Str, Saratov 410028, Russia.
Natalia E ChalykInstitute of Cardiology, Saratov State Medical University, 12 Chernyshevskogo Str, Saratov 410028, Russia.
Victor A KlochkovInstitute of Cardiology, Saratov State Medical University, 12 Chernyshevskogo Str, Saratov 410028, Russia.
Nigel H KyleLycotec Ltd, Granta Park Campus, Cambridge CB21 6GP, UK.
Yuriy K BashmakovLycotec Ltd, Granta Park Campus, Cambridge CB21 6GP, UK.ORCID 0000-0002-2265-3817
Lycotec (United Kingdom) · GBSaratov State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-nine newly diagnosed individuals with Nonalcoholic Fatty Liver Disease (NAFLD) remaining on habitual dietary regimen were supplemented with regular or lycosome formulations of phosphatidylcholine (PC) during a pilot, randomized, double-blinded clinical study. After two months of oral PC intake (450 mg daily) the liver size as well as serum levels of hepatic enzymes and markers of inflammation were evaluated by ultrasonography and biochemical analysis. It was shown that there was a statistically significant reduction of medians for the Mid-Clavicular liver size from 16.0 cm (95/5% CI: 17.1/15.5) to 15.1 cm (95/5% CI: 17.2/14.4,

Identifiers

PMID29805971
PMCPMC5899869
OpenAlexW2794990912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.