ReviewCanadian journal of gastroenterology & hepatology2018
The Effect of Anesthesia on the Immune System in Colorectal Cancer Patients.
Review in Canadian journal of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- Comparison of inhalation and total intravenous anesthesia on inflammatory markers in microdiscectomy: a double-blind study.BMC anesthesiology · 2025Trial
- The immunomodulatory effect of ketamine in colorectal cancer surgery: a randomized-controlled trial.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Trial
- Th1/Th2 cytokine polarization in three different anaesthesia protocols administered to cats undergoing ovariohysterectomy.BMC veterinary research · 2026Article
- Impact of propofol on gastrointestinal cancer outcomes: A review of cellular behavior, growth, and metastasis.World journal of clinical oncology · 2025Review
- A retrospective observational study of risk factors for postoperative meningitis following resection of meningioma.The Journal of international medical research · 2025Observational
- Pain in Colorectal Surgery: How Does It Occur and What Tools Do We Have for Treatment?Journal of clinical medicine · 2023Review
- The Immunomodulatory Effect of Various Anaesthetic Practices in Patients Undergoing Gastric or Colon Cancer Surgery: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Journal of clinical medicine · 2023Review
- Postoperative Changes in Systemic Immune Tolerance Following Major Oncologic versus Minor Maxillofacial Surgery.Cancers · 2023Article
- Influence of Laparoscopic Surgery on Cellular Immunity in Colorectal Cancer: A Systematic Review and Meta-Analysis.Cancers · 2023Review
- Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model.PloS one · 2023Article
- The effect of volatile anesthetics on cellular responses in the microcirculation of free tissue transfers.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2022Review
- Anesthesia and cancer recurrence: an overview.Journal of anesthesia, analgesia and critical care · 2022Review
- Article
- Anesthesia technique and serum cytokine concentrations in the elective cesarean section.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Effect of Dexmedetomidine-Assisted Intravenous Inhalation Combined Anesthesia on Cerebral Oxygen Metabolism and Serum Th1/Th2 Level in Elderly Colorectal Cancer Patients.Frontiers in surgery · 2021Article
- The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: A systematic review and meta-analysis.Surgery open science · 2020Review
- Which idea is better with regard to immune response? Opioid anesthesia or opioid free anesthesia.Journal of inflammation research · 2020Review
- Emerging effect of anesthesia on post-operative tumor recurrence and metastasis.The Journal of international medical research · 2019Review
- Risk factors for postoperative meningitis after microsurgery for vestibular schwannoma.PloS one · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) is the key leading cause of high morbidity and mortality worldwide. Surgical excision is the most effective treatment for CRC. However, stress caused by surgery response can destroy the body's immunity and increase the likelihood of cancer dissemination and metastasis. Anesthesia is an effective way to control the stress response, and recent basic and clinical research has shown that anesthesia and related drugs can directly or indirectly affect the immune system of colorectal cancer patients during the perioperative period. Thus, these drugs may affect the prognosis of CRC surgery patients. This review is intended to summarize currently available data regarding the effects of anesthetics and related drugs on perioperative immune function and postoperative recurrence and metastasis in CRC patients. Determining the most suitable anesthesia for patients with CRC is of utmost importance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.