Evidence map›Paper›PMID 29805946›Full record

ReviewCureus2018

Flawed Reasoning Allows the Persistence of Mainstream Atherothrombosis Theory.

Gregory D Sloop, Gheorghe Pop, Joseph J Weidman, John A St Cyr

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gregory D SloopN/A, Independent Researcher.
Gheorghe PopCardiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands, Nijmegen, NLD.
Joseph J WeidmanN/A, Independent Researcher.
John A St CyrResearch and Development, Jacqmar, Inc., Minneapolis, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deaths due to atherothrombosis are increasing throughout the world except in the lowest socio-demographic stratum. This is despite 60 years of study and expenditure of billions of dollars on lipid theory. Nevertheless, mainstream atherothrombosis theory persists even though it has failed numerous tests. Contrary data are ignored, consistent with the practice of science as envisioned by Thomas Kuhn. This paper examines defects in mainstream atherogenesis theory and the flawed logic which allows its persistence in the face of what should be obvious shortcomings.

Indexed as

ad hocatherothrombosischolesterolinflammationkuhnlipidlogicparadigm shiftpoppertheory

Identifiers

PMID29805946
PMCPMC5969815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.