Evidence map›Paper›PMID 29805787›Full record

ArticleInternational journal of inflammation2018

The Difference in Interleukin-19 Serum on Degrees of Acne Vulgaris Severity.

Moerbono Mochtar, Alamanda Murasmita, M Eko Irawanto, Indah Julianto, Harijono Kariosentono, Fajar Waskito

Open access · goldAbstract read
In one paragraph

Article in International journal of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Moerbono MochtarDermatovenerology Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Indonesia.
Alamanda MurasmitaDermatovenerology Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Indonesia.ORCID 0000-0001-7835-3461
M Eko IrawantoDermatovenerology Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Indonesia.
Indah JuliantoDermatovenerology Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Indonesia.ORCID 0000-0002-4246-4845
Harijono KariosentonoDermatovenerology Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Indonesia.
Fajar WaskitoDermatovenerology Department, Gadjah Mada University, Dr. Sardjito' General Hospital, Yogyakarta, Indonesia.
Sebelas Maret University · IDUniversitas Gadjah Mada · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcne vulgaris is a multifactorial disease. Recent study showed that inflammation does have a central role in the formation of both inflammatory and noninflammatory lesions in acne vulgaris. There are various findings of proinflammatory cytokines related to acne vulgaris, but no previous study correlate interleukin- (IL-) 19 to acne vulgaris. This pilot study aims to look at difference in IL-19 serum concentration on degrees of severity of acne vulgaris.

methodsThis is an analytical observational cross-sectional study. Sample subjects were patients with acne vulgaris who met the inclusion criteria. Enzyme-linked immunosorbent assay (ELISA) study was applied to measure IL-19 serum.

resultAnalysis test found statistically significant difference between IL-19 serum concentration of group of patients with mild acne vulgaris and that of group of patients with severe acne vulgaris. Moreover, analysis revealed significant difference between IL-19 serum concentration of group of patients with moderate acne vulgaris and that of group of patients with severe acne vulgaris.

conclusionsThere are differences in serum levels of IL-19 on the severity of acne vulgaris. The significant difference might show that inflammation has a core role in severity of acne vulgaris, and IL-19 might potentially be related to acne vulgaris.

Identifiers

PMID29805787
PMCPMC5899841
OpenAlexW2794657549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.