Evidence map›Paper›PMID 29805573›Full record

ArticleOncology letters2018

Elevated peripheral blood B lymphocytes and CD3

Hailong Liang, Xiangyang Chu, Jing Zhao, Guosheng Xing, Yingjian Si

Abstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hailong LiangDepartment of Thoracic Surgery, General Hospital of People's Liberation Army, Beijing 100853, P.R. China.
Xiangyang ChuDepartment of Thoracic Surgery, General Hospital of People's Liberation Army, Beijing 100853, P.R. China.
Jing ZhaoDepartment of Thoracic Surgery, General Hospital of Beijing Command, Beijing 100700, P.R. China.
Guosheng XingDepartment of Thoracic Surgery, General Hospital of Beijing Command, Beijing 100700, P.R. China.
Yingjian SiDepartment of Pediatrics, General Hospital of Beijing Command, Beijing 100700, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been established that the tumor microenvironment (TME) has a crucial role in enabling tumors to evade from host immune responses. Previous studies demonstrated that tumor cells are not only able to reshape immune milieu at the tumor site, but also exert systemic effects, which has been demonstrated to be important for metastasis. At present, how the peripheral immune environment change in the tumor-bearing host is unclear. The present study identified a number of changes in the proportions of lymphocyte subpopulations and the levels of cytokines in patients with NSCLC, which may provide a preliminary profile of the immune environment in the peripheral blood of patients harboring a tumor. These findings expand on the present knowledge on how tumors can alter the immune system to benefit its growth and metastasis, which may provide a potential novel strategy for immunotherapy.

Indexed as

immune systemmetastasisnon-small cell lung cancerperipheral immune environmenttumor

Identifiers

PMID29805573
PMCPMC5950528

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.