Evidence map›Paper›PMID 29805519›Full record

ArticleExperimental and therapeutic medicine2018

The effects of doxorubicin-loaded liposomes on viability, stem cell surface marker expression and secretion of vascular endothelial growth factor of three-dimensional stem cell spheroids.

Hyunjin Lee, Jihwan Son, Chae-Bin Na, Gawon Yi, Heebeom Koo, Jun-Beom Park

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. NovelHeliyon · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hyunjin LeeDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Jihwan SonDepartment of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Chae-Bin NaDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Gawon YiDepartment of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Heebeom KooDepartment of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Jun-Beom ParkDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to evaluate the effects of anionic, cationic and neutral liposomes containing doxorubicin on the cellular viability and osteogenic differentiation of three-dimensional stem cell spheroids. Doxorubicin-loaded liposomes were prepared using the traditional thin-lipid-film-hydration method and were characterized using transmission electron microscopy and a zeta potential analyzer. The doxorubicin release profile from these liposomes was also analyzed

Indexed as

bone marrowcell differentiationcell proliferationcellular spheroidsdoxorubicingingivaliposomesstem cells

Identifiers

PMID29805519
PMCPMC5958669
OpenAlexW2797314577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.