Evidence map›Paper›PMID 29805452›Full record

ArticleObstetrics and gynecology international2018

Prevalence and Factors Associated with Hydatidiform Mole among Patients Undergoing Uterine Evacuation at Mbarara Regional Referral Hospital.

Olivier Mulisya, Drucilla J Roberts, Elizabeth S Sengupta, Elly Agaba, Damaris Laffita, Tusabe Tobias, Derrick Paul Mpiima, Lugobe Henry, Ssemujju Augustine, Masinda Abraham and 2 more

Open access · goldAbstract read
In one paragraph

Article in Obstetrics and gynecology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Olivier MulisyaUniversity of Goma, Goma, Democratic Republic of the Congo.ORCID 0000-0002-4777-368X
Drucilla J RobertsDepartment of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
Elizabeth S SenguptaDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Elly AgabaMbarara University of Science and Technology, Mbarara, Uganda.
Damaris LaffitaMbarara University of Science and Technology, Mbarara, Uganda.
Tusabe TobiasDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Derrick Paul MpiimaMbarara University of Science and Technology, Mbarara, Uganda.ORCID 0000-0003-0112-4403
Lugobe HenryMbarara University of Science and Technology, Mbarara, Uganda.ORCID 0000-0001-8177-8786
Ssemujju AugustineMbarara University of Science and Technology, Mbarara, Uganda.
Masinda AbrahamMbarara University of Science and Technology, Mbarara, Uganda.
Twizerimana HillaryMbarara University of Science and Technology, Mbarara, Uganda.
Julius MugishaMakerere University, Kampala, Uganda.
Mbarara University of Science and Technology · UGIndiana University School of MedicineMakerere University · UGMassachusetts General Hospital · USUniversity of Goma · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe sought to determine the prevalence of and factors associated with hydatidiform molar gestations amongst patients undergoing uterine evacuation at Mbarara Regional Referral Hospital (MRRH), Mbarara, Uganda.

methodsThis was a cross-sectional study carried out from November 2016 to February 2017. All patients admitted for uterine evacuation for nonviable pregnancy were included. The study registered 181 patients. Data were collected on sociodemographics, medical conditions, obstetrics, and gynecological factors. The evacuated tissue received a full gross and histopathologic examination. Cases of pathologically suspected complete hydatidiform mole were confirmed by p57 immunohistochemistry. Data were analyzed using STATA 13.

resultsThe prevalence of hydatidiform mole was 6.1% (11/181). All detected moles were complete hydatidiform moles, and there were no diagnosed partial hydatidiform moles. Clinical diagnosis of molar pregnancy was suspected in 13 patients, but only 69.2% (9/13) were confirmed as molar pregnancies histologically. Two cases were clinically unsuspected. Factors that had a significant relationship with complete hydatidiform mole included maternal age of 35 years and above (aOR 13.5; CI: 1.46-125.31;

conclusionThe prevalence of complete hydatidiform mole was high at 6.1%. Associated risk factors included advanced maternal age (35 years and above), history of previous abortions, and gestational age beyond the first trimester at the time of evacuations. RECOMMENDATIONS: We recommend putting in place capacity to do routine histopathological examination of all products of conception especially those at high risk for a molar gestation either by clinical suspicion or by risk factors including advanced maternal age, advanced gestational age, and history of previous abortion because of high prevalence of complete mole.

Identifiers

PMID29805452
PMCPMC5901474
OpenAlexW2794620186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.