ArticlePakistan journal of medical sciences
Surgical outcomes of nephrectomy for elderly patients with renal cell carcinoma.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Review
- Temporal trends and demographic-geographic disparities in kidney Cancer mortality in the United States, 1999-2023.Preventive medicine reports · 2025Article
- Comparison of the effects of transperitoneal and retroperitoneal robot-assisted partial nephrectomy.Pakistan journal of medical sciences · 2024Article
- Efficacy and feasibility of robot-assisted partial nephrectomy for octogenarians: comparison with younger counterparts.Journal of robotic surgery · 2022Article
- Perioperative outcomes in elderly patients undergoing nephrectomy for renal cell carcinoma.Research and reports in urology · 2019Article
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4 authors.
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Abstract
objectiveThe feasibility of curative surgery for elderly patients with renal cell carcinoma (RCC) remains controversial and under discussion. The main aim of this study was to evaluate the long-term benefits of curative surgery as a treatment for RCC in elderly patients.
methodsWe retrospectively considered 672 patients with RCC who underwent partial nephrectomy or radical nephrectomy between January 2004 and July 2014. X-tile program was used to determine the optimal age cutoff values with CSS as endpoint.
resultsPatients were divided into the following groups according to their age using the method of X-tile program: a young group (< 40 years), a young-old group (40-75) and an old-old group (≥ 75). Following multivariate analysis age ≥ 75 years was determined to be an independent risk factor for overall survival (HR=4.36; 95% CI: 1.31-14.48; P=0.016); interestingly, this was not the case for cancer-specific survival (HR = 2.65; 95%CI: 0.77-9.16; P=0.124). Furthermore, an age of 40 to 75 years was not a risk factor according to univariate and multivariate analysis.
conclusionAfter determining the age cutoff values, there was no significant difference in prognosis between young and old patients with RCC.
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