ArticleDementia and geriatric cognitive disorders extra
Frontal White Matter Hyperintensity Is Associated with Verbal Aggressiveness in Elderly Women with Alzheimer Disease and Amnestic Mild Cognitive Impairment.
Article in Dementia and geriatric cognitive disorders extra. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Seeking the neural basis of neuropsychiatric symptoms in dementia: neuroimaging findings and controversies.Frontiers in aging neuroscience · 2025Review
- Correlation between white matter hyperintensity and delusional symptoms in Alzheimer's disease.BMC psychiatry · 2023Article
- The Longitudinal Assessment of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Alzheimer's Disease and Their Association With White Matter Hyperintensities in the National Alzheimer's Coordinating Center's Uniform Data Set.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- Agitation and impulsivity in mid and late life as possible risk markers for incident dementia.Alzheimer's & dementia (New York, N. Y.) · 2020Review
- Volume of white matter hyperintensities increases with blood pressure in patients with hypertension.The Journal of international medical research · 2019Article
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Authors and funding
8 authors.
Funding
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Abstract
BACKGROUND/
aimsBehavioral and psychological symptoms of dementia (BPSD) are exhibited in most patients with Alzheimer disease (AD). Although white matter hyperintensity (WMH) is often observed with AD, the precise role of WMH in BPSD remains unclear. The current study aimed to identify the impact of regional WMH on specific features of BPSD in persons with mild to moderate AD and amnestic mild cognitive impairment (aMCI).
methodsA sample of 256 female outpatients with AD (
resultsWhole-brain WMH was associated with verbal aggressiveness. In multivariate analysis, PVH in the frontal lobe was independently associated with verbal aggressiveness after adjustment for brain atrophy and clinical confounders.
conclusionThe current results indicated that PVH in the frontal lobe was independently associated with verbal aggressiveness.
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