Evidence map›Paper›PMID 29805312›Full record

SynthesisMediators of inflammation2018

Therapeutic Effects of Medicinal Plants on Cutaneous Wound Healing in Humans: A Systematic Review.

Tarcisio Vitor Augusto Lordani, Celia Eliane de Lara, Fabiana Borges Padilha Ferreira, Mariana de Souza Terron Monich, Claudinei Mesquita da Silva, Claudia Regina Felicetti Lordani, Fernanda Giacomini Bueno, Jorge Juarez Vieira Teixeira, Maria Valdrinez Campana Lonardoni

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Pooled it
  2. Article
  3. Frontiers in bioinformatics · 2026
    Article
  4. Review
  5. Phytochemical Analysis and Therapeutic Potential ofPlants (Basel, Switzerland) · 2025
    Article
  6. Biological Effects ofPlants (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Ferulic Acid: A Review of Mechanisms of Action, Absorption, Toxicology, Application on Wound Healing.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Guiding stem cells for cutaneous repair.Current research in pharmacology and drug discovery · 2023
    Review
  18. Antioxidants (Basel, Switzerland) · 2022
    Article
  19. Wound healing activity ofVeterinary world · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tarcisio Vitor Augusto LordaniPostgraduate Program in Bioscience and Pathophysiology, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.ORCID 0000-0002-9997-6809
Celia Eliane de LaraPostgraduate Program in Bioscience and Pathophysiology, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.
Fabiana Borges Padilha FerreiraPostgraduate Program in Health Sciences, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.
Mariana de Souza Terron MonichPostgraduate Program in Health Sciences, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.
Claudinei Mesquita da SilvaPostgraduate Program in Health Sciences, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.
Claudia Regina Felicetti LordaniDepartment of Clinical Nutrition, Universidade Estadual do Oeste do Paraná, Rua Universitária 1619, Universitário, 85819-110 Cascavel, PR, Brazil.
Fernanda Giacomini BuenoMedical and Pharmaceutical Science Center, Universidade Estadual do Oeste do Paraná, Rua Universitária 1619, Universitário, 85819-110 Cascavel, PR, Brazil.
Jorge Juarez Vieira TeixeiraDepartment of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.
Maria Valdrinez Campana LonardoniDepartment of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil.ORCID 0000-0003-2185-4163
Universidade Estadual de Maringá · BRUniversidade Estadual do Oeste do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmaceutical industry has made great strides in providing drugs that are able to stimulate the healing process, but only 1-3% of all drugs that are listed in Western pharmacopoeias are intended for use on the skin or cutaneous wounds. Of these, at least one-third are obtained from plants. We sought to review the therapeutic effects of medicinal plants on human skin lesions. For this systematic review, we searched the PubMed, Scopus, and Web of Science databases to identify clinical trials that were published from 1997 to 2017. We reviewed studies that described the use of medicinal plants for the treatment of skin lesions in humans. Ten studies were selected, eight of which were published from 2007 to 2016, with a total of 503 patients. Among the plant species that were used for the treatment of human skin lesions, 12 belonged to 11 families and were included in the analysis. All of the plant species that were studied presented high therapeutic potential for the treatment of cutaneous lesions.

Indexed as

AnimalsHumansPhytotherapyPlants, MedicinalSkin DiseasesWound Healing

Identifiers

PMID29805312
PMCPMC5901822
OpenAlexW2795311515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.