Evidence map›Paper›PMID 29805302›Full record

ArticleInternational journal of biological sciences2018

DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.

Ying Zhang, Guangpei Chen, Zhen Gu, Haijian Sun, Andrew Karaplis, David Goltzman, Dengshun Miao

Abstract read
In one paragraph

Article in International journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying ZhangState Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Guangpei ChenState Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Zhen GuState Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Haijian SunState Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Andrew KaraplisDepartment of Medicine, McGill University, Canada.
David GoltzmanDepartment of Medicine, McGill University, Canada.
Dengshun MiaoState Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.

Funding

CIHR
6 · The paper itself

Abstract

We previously demonstrated that parathyroid hormone-related peptide (PTHrP) 1-84 knockin (

Indexed as

Bone DevelopmentDNA DamageAnimalsAntioxidantsApoptosisBone ResorptionCell Cycle CheckpointsCell ProliferationCellular SenescenceCheckpoint Kinase 2FemaleGene DeletionGene Expression ProfilingHistonesMaleMiceAntioxidantsCheckpoint Kinase 2Chek2 protein, mousegamma-H2AX protein, mouseHistonesParathyroid Hormone-Related ProteinReactive Oxygen SpeciesTrp53 protein, mouseTumor Suppressor Protein p53Chk2osteoblastic bone formationPTHrPskeletal growth

Identifiers

PMID29805302
PMCPMC5968843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.