Evidence map›Paper›PMID 29805276›Full record

ArticleKorean journal for food science of animal resources2018

Investigation of the Protective Effect of Kefir against Isoproterenol Induced Myocardial Infarction in Rats.

Handan Mert, Hikmet Yılmaz, Kıvanç Irak, Serkan Yıldırım, Nihat Mert

Open access · greenAbstract read
In one paragraph

Article in Korean journal for food science of animal resources, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Indole-alkaloid-rich fraction ofBiotechnology reports (Amsterdam, Netherlands) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Handan MertDepartment of Biochemistry, Yuzuncu Yil University, Faculty of Veterinary Medicine, Van 65090, Turkey.
Hikmet YılmazDepartment of Biochemistry, Yuzuncu Yil University, Faculty of Veterinary Medicine, Van 65090, Turkey.
Kıvanç IrakDepartment of Biochemistry, Siirt University, Faculty of Veterinary Medicine, Siirt, 56100, Turkey.
Serkan YıldırımDepartment of Pathology, Ataturk University, Faculty of Veterinary Medicine, Erzurum, 25030, Turkey.
Nihat MertDepartment of Biochemistry, Yuzuncu Yil University, Faculty of Veterinary Medicine, Van 65090, Turkey.
Van Yüzüncü Yıl Üniversitesi · TRAtatürk University · TRSiirt Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate the protective effects of kefir against myocardial infarction induced by isoproterenol (ISO). The rats were randomly divided into 4 groups, each group consisting of 8 rats. The control group, the kefir group (5 mL/kg/d kefir administered to rats as intra-gastric gavage for 60 d), the ISO group (100 mg/kg ISO was administered to rats, s.c. on 61. and 62. d), and kefir+ISO group (5 mL/kg/d kefir was administered to rats intra gastric gavage for 60 days prior to ISO, 100 mg/kg in two doses on day 61 and 62). 12 h after the last ISO dose, all rats were decapitated and their blood samples were collected. Cardiac tissue was reserved for histopathological examination. creatine kinase (CK), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), triglycerides, total cholesterol,very low density lipoprotein (VLDL), low density lipoprotein (LDL), high density lipoprotein (HDL) and glucose were measured by autoanalyzer, whole blood malondialdehyde (MDA), glutathione (GSH) and plasma advanced oxidation protein products (AOPP) levels were measured spectrophotometrically. It was determined that in the group of kefir+ISO, the levels of AST (

Indexed as

antioxidantcardiac markerisoproterenolkefirmyocardial infarction

Identifiers

PMID29805276
PMCPMC5960824
OpenAlexW2892422561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.