SynthesisJournal of the American Dental Association (1939)2018
Controlling caries in exposed root surfaces with silver diamine fluoride: A systematic review with meta-analysis.
Synthesis in Journal of the American Dental Association (1939), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07194629 (Impact of Silver Diamine Fluoride), which is not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Silver Diamine Fluoride (SDF) 38% Application on the Oral Health of the Elderly With Loss of Autonomy Living in Long-term Care Homes (CHSLDs): A Pilot and Feasibility Effectiveness Study
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- Silver diamine fluoride for managing carious lesions: an umbrella review.BMC oral health · 2019Pooled it
- Influence of knowledge about silver diamine fluoride on the acceptance and perception of Brazilian children's guardians: a randomized controlled clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Trial
- Potential Applications of Nano Silver Fluoride in the Prevention of Dental Caries in Older Adults: A Scoping Review.Gerodontology · 2026Article
- Dental Caries in Older Adults: A Narrative Review for Non-Dental Providers.International journal of environmental research and public health · 2026Review
- Bridging the Gap Between Knowledge and Practice: Contemporary Preventive Strategies in Modern Dental Care-A Cross-Sectional Survey of Practicing Dentists.Journal of clinical medicine · 2026Article
- Efficacy of topical strategies to prevent the onset of root caries lesions: an in vitro study.Odontology · 2026Article
- Comparative Evaluation of the Effect of Different Concentrations of Silver Diamine Fluoride on the Shear Bond Strength of Composite Resin on Primary Tooth Dentin: AnInternational journal of clinical pediatric dentistry · 2026Article
- In vitro evaluation of the effects of various remineralization agents on root caries.BMC oral health · 2025Article
- Effect of Silver Diamine Fluoride Application Methods on Dentin Microhardness and Durability Under pH Cycling: An In Vitro Study.Clinical and experimental dental research · 2025Article
- Assessment of Trends in Non-Restorative and Preventative Dental Treatment Pre- and Post-COVID-19: A Health Informatics Pilot Study.Children (Basel, Switzerland) · 2025Article
- Dentists' knowledge, attitude and practice towards silver diamine fluoride therapy in Hong Kong: a mixed-method study.Frontiers in oral health · 2024Article
- Bonding performance of glass ionomer cement to carious dentin treated with different surface treatment protocols using silver diamine fluoride.Scientific reports · 2023Article
- pH-Responsive Biomaterials for the Treatment of Dental Caries-A Focussed and Critical Review.Pharmaceutics · 2023Review
- The Prevention, Diagnosis, and Treatment of Rapid Oral Health Deterioration (ROHD) among Older Adults.Journal of clinical medicine · 2023Article
- Silver diamine fluoride therapy for dental care.The Japanese dental science review · 2022Review
- Effectiveness of 38% Silver Diamine Fluoride Application along with Atraumatic Restorative Treatment for Arresting Caries in Permanent Teeth When Compared to Atraumatic Restorative Treatment in Adults-Study Protocol for a Randomized Controlled Trial.Methods and protocols · 2022Article
- Color changes and shear bond strength to simulated caries lesions treated with a novel solution of 20% silver nanoclusters in polymethacrylic acid.Scientific reports · 2022Article
- Knowledge, Practices and Attitudes towards Silver Diamine Fluoride Therapy among Dentists in Japan: A Mixed Methods Study.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundIn this systematic review, the authors aim to assess the effect of silver diamine fluoride (SDF) in preventing and arresting caries in exposed root surfaces of adults. TYPES OF STUDIES REVIEWED: Two reviewers independently searched for controlled clinical trials with at least 12 months of follow-up, without language or date of publication restraints, in 8 electronic databases, 5 registries of ongoing trials, and reference lists of narrative reviews.
resultsThe authors found 2,356 unique records and included 3 trials in which the investigators randomly assigned 895 older adults. Investigators in all studies compared SDF with placebo; investigators in 1 also compared 38% SDF with chlorhexidine and sodium fluoride varnishes. The primary effect measures were the weighted mean differences (WMDs) in decayed or filled root surfaces (DFRS) and the mean differences in arrested carious lesions between SDF and control groups. The studies had low risk of bias in most domains. SDF applications had a significantly better preventive effect in comparison with placebo (WMD DFRS: 24 months, -0.56; 95% confidence interval, -0.77 to -0.36; 30 months or more, -0.80; 95% confidence interval, -1.19 to -0.42), and they were as effective as either chlorhexidine or sodium fluoride varnish in preventing new root carious lesions. SDF also provided a significantly higher caries arrest effect than did placebo (pooled results not calculated). Complaints about black staining of the carious lesions by SDF were rare among older adults. CONCLUSIONS AND PRACTICAL IMPLICATIONS: Yearly 38% SDF applications to exposed root surfaces of older adults are a simple, inexpensive, and effective way of preventing caries initiation and progression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.