Evidence map›Paper›PMID 29804145›Full record

ArticleLung2018

Residual Renal Function and Obstructive Sleep Apnea in Peritoneal Dialysis: A Pilot Study.

Aviya Lanis, Eric Kerns, Susie L Hu, Margaret H Bublitz, Patricia Risica, Susan Martin, Jeffrey Parker, Richard Millman, Lance D Dworkin, Ghada Bourjeily

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Functional outcomes of sleep predict cardiovascular intermediary outcomes and all-cause mortality in patients on incident hemodialysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  5. APD or CAPD: one glove does not fit all.International urology and nephrology · 2021
    Review
  6. Automated Peritoneal Dialysis: Patient Perspectives and Outcomes.International journal of nephrology and renovascular disease · 2021
    Review
  7. Risk, Severity, and Predictors of Obstructive Sleep Apnea in Hemodialysis and Peritoneal Dialysis Patients.International journal of environmental research and public health · 2018
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Aviya LanisAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA.
Eric KernsAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA.
Susie L HuAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA.
Margaret H BublitzAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA.
Patricia RisicaCenter for Health Equity Research, Brown School of Public Health, 121 South Main Street, Providence, RI, USA.
Susan MartinThe Miriam Hospital, 164 Summit Avenue, Providence, RI, USA.
Jeffrey ParkerRhode Island Hospital Sleep Disorder Center, 450 Veterans Memorial Parkway, East Providence, RI, USA.
Richard MillmanAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA.
Lance D DworkinAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA.
Ghada BourjeilyAlpert Medical School of Brown University, 222 Richmond Street, Providence, RI, USA. ghada_bourjeily@brown.edu.ORCID http://orcid.org/0000-0002-0543-4719
Providence College · USBrown University · USRhode Island Hospital · US

Funding

Placental role in mediating adverse outcomes in obstructive sleep apneaR01HD078515 · NICHD · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2014 to 2018
$2.7M
Predictors of de novo development of obstructive sleep apnea in pregnancyR01HL130702 · NHLBI · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2016 to 2020
$2.6M
NHLBI NIH HHS R01 HL130702NICHD NIH HHS R01 HD078515
6 · The paper itself

Abstract

purposeObstructive sleep apnea is common in patients with end-stage renal disease, and there is increasing evidence that clinical factors specific to end-stage renal disease contribute pathophysiologically to obstructive sleep apnea. It is not known whether circumstances specific to dialysis modality, in this case peritoneal dialysis, affect obstructive sleep apnea. Our study aimed to investigate the prevalence of obstructive sleep apnea in the peritoneal dialysis population and the relevance of dialysis-specific measures and kidney function in assessing this bidirectional relationship.

methodsParticipants with end-stage renal disease who were treated with nocturnal automated peritoneal dialysis for at least 3 months were recruited from a hospital-based dialysis center. Laboratory measures of dialysis adequacy, peritoneal membrane transporter status, and residual renal function were gathered by chart review. Patients participated in a home sleep apnea test using a level III sleep apnea monitor.

resultsOf fifteen participants recruited, 33% had obstructive sleep apnea diagnosed by apnea-hypopnea index ≥ 5 events per hour of sleep. Renal creatinine clearance based upon 24-h urine collection was negatively correlated with apnea-hypopnea index (ρ = - 0.63, p = 0.012). There were no significant associations between anthropometric measures, intra-abdominal dwell volume, or peritoneal membrane transporter status and obstructive sleep apnea measures.

conclusionsThe prevalence of obstructive sleep apnea and sleep disturbances is high in participants receiving peritoneal dialysis. Elevated apnea-hypopnea index is associated with lower residual renal function, whereas dialysis-specific measures such as intra-abdominal dwell volume and peritoneal membrane transporter status do not correlate with severity of obstructive sleep apnea.

Indexed as

AdultAgedFemaleHumansKidneyKidney Failure, ChronicMaleMiddle AgedPeritoneal DialysisPilot ProjectsPrevalenceRhode IslandRisk FactorsSeverity of Illness IndexSleep Apnea, ObstructiveTime FactorsDialysisObstructive sleep apneaPeritoneal dialysisSleep-disordered breathing

Identifiers

PMID29804145
PMCPMC6556060
OpenAlexW2803141758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.