ArticleBMJ open2018
Cancer recording in patients with and without type 2 diabetes in the Clinical Practice Research Datalink primary care data and linked hospital admission data: a cohort study.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Maternal diabetes and risk of childhood malignancies in the offspring: a systematic review and meta-analysis of observational studies.Acta diabetologica · 2021Pooled it
- Prostate-specific antigen testing and opportunistic prostate cancer screening: a cohort study in England, 1998-2017.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- The association between pre-existing type 2 diabetes on cancer-related and all-cause mortality among women with breast cancer.Breast cancer research and treatment · 2026Article
- Article
- Long-term healthcare use after postoperative complications: an analysis of linked primary and secondary care routine data.BJA open · 2023Article
- Sodium-Glucose Cotransporter 2 Inhibitors and the Short-term Risk of Bladder Cancer: An International Multisite Cohort Study.Diabetes care · 2022Article
- Thiazolidinediones and Glucagon-Like Peptide-1 Receptor Agonists and the Risk of Nonalcoholic Fatty Liver Disease: A Cohort Study.Hepatology (Baltimore, Md.) · 2021Observational
- Predictive values for different cancers and inflammatory bowel disease of 6 common abdominal symptoms among more than 1.9 million primary care patients in the UK: A cohort study.PLoS medicine · 2021Article
- Article
- Real-world evidence: the devil is in the detail.Diabetologia · 2020Review
- Public preferences regarding data linkage for research: a discrete choice experiment comparing Scotland and Sweden.BMC medical informatics and decision making · 2020Article
- Using the Risk Factors of Pancreatic Cancer and Their Interactions in Cancer Screening: A Case-Control Study in Shanghai, China.Annals of global health · 2019Article
- Identifying incident cancer cases in dispensing claims: A validation study using Australia's Repatriation Pharmaceutical Benefits Scheme (PBS) data.International journal of population data science · 2019Article
- Incretin based drugs and risk of cholangiocarcinoma among patients with type 2 diabetes: population based cohort study.BMJ (Clinical research ed.) · 2018Article
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Authors and funding
6 authors.
Funding
Abstract
OBJECTIVES AND
settingConflicting results from studies using electronic health records to evaluate the associations between type 2 diabetes and cancer fuel concerns regarding potential biases. This study aimed to describe completeness of cancer recording in UK primary care data linked to hospital admissions records.
designPatients aged 40+ years with insulin or oral antidiabetic prescriptions in Clinical Practice Research Datalink (CPRD) primary care without type 1 diabetes were matched by age, sex and general practitioner practice to non-diabetics. Those eligible for linkage to Hospital Episode Statistics Admitted Patient Care (HES APC), and with follow-up during April 1997-December 2006 were included. PRIMARY AND SECONDARY OUTCOME MEASURES: Cancer recording and date of first record of cancer were compared. Characteristics of patients with cancer most likely to have the diagnosis recorded only in a single data source were assessed. Relative rates of cancer estimated from the two datasets were compared.
participants53 585 patients with type 2 diabetes matched to 47 435 patients without diabetes were included.
resultsOf all cancers (excluding non-melanoma skin cancer) recorded in CPRD, 83% were recorded in HES APC. 94% of cases in HES APC were recorded in CPRD. Concordance was lower when restricted to same-site cancer records, and was negatively associated with increasing age. Relative rates for cancer were similar in both datasets.
conclusionsGood concordance in cancer recording was found between CPRD and HES APC among type 2 diabetics and matched controls. Linked data may reduce misclassification and increase case ascertainment when analysis focuses on site-specific cancers.
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