Evidence map›Paper›PMID 29802723›Full record

ArticleClinical cardiology2018

Prevalence and outcome of patients referred for chest pain with high-sensitivity troponin elevation and no diagnosis at discharge.

Vincent Lordet, Matthieu Lesbordes, Rodrigue Garcia, Nicolas Varroud-Vial, Pierre Ingrand, Luc Christiaens, Sébastien Levesque

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In one paragraph

Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Vincent LordetDepartment of Cardiology, CHU of Poitiers, Poitiers, France.ORCID http://orcid.org/0000-0001-9923-8104
Matthieu LesbordesDepartment of Cardiology, CHU of Poitiers, Poitiers, France.
Rodrigue GarciaDepartment of Cardiology, CHU of Poitiers, Poitiers, France.
Nicolas Varroud-VialDepartment of Cardiology, CHU of Poitiers, Poitiers, France.
Pierre IngrandINSERM CIC-1402, Department of Epidemiology and Biostatistics, Poitiers University, Poitiers, France.
Luc ChristiaensDepartment of Cardiology, CHU of Poitiers, Poitiers, France.
Sébastien LevesqueDepartment of Cardiology, CHU of Poitiers, Poitiers, France.
Centre Hospitalier Universitaire de Poitiers · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpecialized chest pain units appear to increase the proportion of patients with acute chest pain who are properly evaluated, but some of them remain doubtful. HYPOTHESIS: The aim of this study was to evaluate the survival and occurrence of cardiovascular events in patients without diagnosis at the end of management of chest pain with high-sensitivity troponin (Tn) elevation.

methodAll consecutive patients who came to the cardiac emergency room of Poitiers University Hospital between January 1, 2014, and August 7, 2015, for chest pain and Tn elevation were included. The primary endpoint was the number of undiagnosed patients; secondary endpoints included survival and major adverse cardiac events.

resultsA total of 1001 patients (695 male; mean age, 68 ±16 years) who had chest pain and Tn elevation were included. Median follow-up was 24.5 (IQR, 14.7-29.5) months. Forty-seven (4.7%) patients remained without diagnosis. Compared with patients with diagnosis, these patients were younger (53.6 ±19.7 years; P < 0.0001) and had less hypertension (29.8%; P < 0.0001), diabetes (4.3%; P = 0.0016), and history of coronary artery disease (6.4%; P < 0.0001). No patients died or experienced MACE in 6-month follow-up. Survival curves showed the probability of survival was excellent, not only at 6 months, but also at 36 months (P = 0.0025).

conclusionsLess than 5% of patients referred for chest pain and with high-sensitivity Tn elevation remained without diagnosis after adapted care in the chest pain unit. Their 6-month prognosis was excellent.

Indexed as

ElectrocardiographyReferral and ConsultationAgedBiomarkersChest PainComputed Tomography AngiographyCoronary AngiographyDiagnosis, DifferentialFemaleFollow-Up StudiesFranceHumansMaleMiddle AgedPatient DischargePrevalenceBiomarkersTroponinAcute Coronary SyndromeChest Pain UnitTroponinUndiagnosed; MACE

Identifiers

PMID29802723
PMCPMC6489751
OpenAlexW2803515183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.