Evidence map›Paper›PMID 29802647›Full record

ArticleJournal of gastroenterology and hepatology2018

Trends in incidence and survival of esophageal cancer in Korea: Analysis of the Korea Central Cancer Registry Database.

Aesun Shin, Young-Joo Won, Hye-Kyung Jung, Hyun-Joo Kong, Kyu-Won Jung, Chang-Mo Oh, Sunho Choe, Jihyun Lee

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of gastroenterology and hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3'3-diindolylmethane suppresses esophageal cancer tumorigenesis.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Aesun ShinDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Young-Joo WonCancer Registration and Statistics Branch, National Cancer Center, Goyang, Gyeonggi-do, Korea.
Hye-Kyung JungDepartment of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID http://orcid.org/0000-0002-6653-5214
Hyun-Joo KongCancer Registration and Statistics Branch, National Cancer Center, Goyang, Gyeonggi-do, Korea.
Kyu-Won JungCancer Registration and Statistics Branch, National Cancer Center, Goyang, Gyeonggi-do, Korea.
Chang-Mo OhCancer Registration and Statistics Branch, National Cancer Center, Goyang, Gyeonggi-do, Korea.ORCID http://orcid.org/0000-0002-5709-9350
Sunho ChoeDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jihyun LeeDepartment of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.
National Cancer Center · KREwha Womans University · KRSeoul National University · KRKyung Hee University · KR

Funding

National Cancer Center NCC-1610200
6 · The paper itself

Abstract

BACKGROUND AND

aimThe diagnostic and therapeutic modalities of esophageal cancer have recently improved in Asia, and its prognosis is expected to change. This study provides a population-based report on the epidemiology of esophageal cancer in Korea.

methodsCancer incidence data from 1999 to 2013 were obtained from the Korea Central Cancer Registry, covering the entire population. Age-standardized incidence rates and annual percent changes were calculated according to subsites and histological types. Five-year relative survival rates were estimated for cases diagnosed between 1993 and 2013. Relative excess rates were compared between patients diagnosed from 2009 to 2013 and 2006 to 2008.

resultsThe age-standardized incidence rates decreased from 8.8 per 100 000 populations in 1999 to 5.9 in 2013 with an annual percent change of -2.6% in men and -2.2% in women. The most common histological type was squamous cell carcinoma, accounting for 90.2% of all esophageal cancers in 2013, followed by adenocarcinomas (3.1%), and their incidences decreased. The proportion of localized and regional cancer tended to increase compared with that of distant cancer. Five-year relative survival of squamous cell carcinoma improved from 12.1% (1993-1995) to 34.6% (2009-2013). Relative excess rate was 0.72 (95% confidence interval 0.65-0.80) in localized stage and 0.88 (95% confidence interval, 0.82-0.95) in regional stage comparing patients diagnosed from 2009 to 2013 and 2006 to 2008.

conclusionsThe incidence of esophageal cancer has decreased in Korea for the past 15 years, and 5-year survival rates have improved significantly. These increases may be attributable to more effective detection of early-stage disease.

Indexed as

AdenocarcinomaAdolescentAdultAgedAge DistributionChildChild, PreschoolDatabases, FactualEarly Detection of CancerEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFemaleHumansIncidenceInfantInfant, Newborncancer incidencecancer registryesophageal cancersurvival rates

Identifiers

PMID29802647
PMCPMC6334276
OpenAlexW2804401137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.