ArticleMagnetic resonance in medicine2018
Reproducibility of 2D GluCEST in healthy human volunteers at 7 T.
Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diminished reward responsiveness is associated with lower reward network GluCEST: an ultra-high field glutamate imaging study.Molecular psychiatry · 2021Pooled it
- A quantitative meta-analysis of brain glutamate metabolites in aging.Neurobiology of aging · 2020Pooled it
- Transformer Enabled Half Z‑spectrum Sampling BChemical & biomedical imaging · 2026Article
- Characterizing Spatial Associations Between GluCEST MRI and Neurotransmitter Receptor Density in the Human Cortex.Human brain mapping · 2025Article
- Application of 5T glutamate chemical exchange saturation transfer imaging in brain tumors: preliminary results.Journal of neuro-oncology · 2024Article
- In vivoMagnetic resonance in medicine · 2024Article
- Mapping hippocampal glutamate in healthy aging withFrontiers in aging neuroscience · 2024Article
- Application of glutamate weighted CEST in brain imaging of nicotine dependent participants in vivo at 7T.PloS one · 2024Article
- Amine-weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors.NMR in biomedicine · 2023Article
- Reproducibility of 3 T APT-CEST in Healthy Volunteers and Patients With Brain Glioma.Journal of magnetic resonance imaging : JMRI · 2023Article
- Repeatability of BMagnetic resonance in medicine · 2022Article
- IntegratingNeuroImage · 2022Article
- Friend or Foe? Defining the Role of Glutamate in Aging and Alzheimer's Disease.Frontiers in aging · 2022Review
- Emerging MR Imaging and Spectroscopic Methods to Study Brain Tumor Metabolism.Frontiers in neurology · 2022Review
- Glutamate Chemical Exchange Saturation Transfer (GluCEST) Magnetic Resonance Imaging of Rat Brain With Acute Carbon Monoxide Poisoning.Frontiers in neurology · 2022Article
- Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo.Current opinion in chemical biology · 2021Review
- Recovery kinetics of creatine in mild plantar flexion exercise using 3D creatine CEST imaging at 7 Tesla.Magnetic resonance in medicine · 2021Article
- Accelerating GluCEST imaging using deep learning for BMagnetic resonance in medicine · 2020Article
- Regional Mapping of Brain Glutamate Distributions Using Glutamate-Weighted Chemical Exchange Saturation Transfer Imaging.Diagnostics (Basel, Switzerland) · 2020Article
- Glutamate-Weighted CEST Contrast After Removal of Magnetization Transfer Effect in Human Brain and Rat Brain with Tumor.Molecular imaging and biology · 2020Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
purposeTo investigate the reproducibility of gray and white matter glutamate contrast of a brain slice among a small group of healthy volunteers by using the 2D single-slice glutamate CEST (GluCEST) imaging technique.
methodsSix healthy volunteers were scanned multiple times for within-day and between-day reproducibility. One more volunteer was scanned for within-day reproducibility at 7T MRI. Glutamate CEST contrast measurements were calculated for within subjects and among the subjects and the coefficient of variations are reported.
resultsThe GluCEST measurements were highly reproducible in the gray and white matter area of the brain slice, whether it was within-day or between-day with a coefficient of variation of less than 5%.
conclusionThis preliminary study in a small group of healthy volunteers shows a high degree of reproducibility of GluCEST MRI in brain and holds promise for implementation in studying age-dependent changes in the brain.
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