Evidence map›Paper›PMID 29802587›Full record

ArticleLasers in medical science2018

Enhancing the effects of chemotherapy by combined macrophage-mediated photothermal therapy (PTT) and photochemical internalization (PCI).

Rohit Kumar Nair, Catherine Christie, David Ju, Diane Shin, Aftin Pomeroy, Kristian Berg, Qian Peng, Henry Hirschberg

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rohit Kumar NairBeckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Rd, Irvine, CA, 92617, USA.
Catherine ChristieBeckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Rd, Irvine, CA, 92617, USA.
David JuBeckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Rd, Irvine, CA, 92617, USA.
Diane ShinBeckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Rd, Irvine, CA, 92617, USA.
Aftin PomeroyBeckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Rd, Irvine, CA, 92617, USA.
Kristian BergDepartment of Radiation Biology, University of Oslo, Montebello, 0310, Oslo, Norway.
Qian PengPathology Clinic, Rikshospitalet-Radiumhospitalet HF Medical Center, University of Oslo, Montebello, 0310, Oslo, Norway.
Henry HirschbergBeckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Rd, Irvine, CA, 92617, USA. hhirschb@uci.edu.
Beckman Laser Institute and Medical Clinic · USUniversity of Oslo · NO

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI VENUGOPALAN, VASAN · 2012 to 2017
$7.0M
NIBIB NIH HHS P41 EB015890
6 · The paper itself

Abstract

Light-based treatment modalities such as photothermal therapy (PTT) or photochemical internalization (PCI) have been well documented both experimentally and clinically to enhance the efficacy of chemotherapy. The main purpose of this study was to examine the cytotoxic effects of silica-gold nanoshell (AuNS)-loaded macrophage-mediated (Ma

Indexed as

Hyperthermia, InducedPhototherapyAnimalsBleomycinCarcinoma, Squamous CellCell Line, TumorEndocytosisGoldHumansMacrophagesNanoshellsPhotosensitizing AgentsPolyethylene GlycolsRatsBleomycinGoldPhotosensitizing AgentsPolyethylene GlycolsGold-silica nanoshellsPhotochemical internalizationPhotothermal therapyRat macrophagesSquamous cell carcinoma

Identifiers

PMID29802587
PMCPMC6296383
OpenAlexW2804564257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.