ReviewInternal and emergency medicine2018
Acute liver injury following Garcinia cambogia weight-loss supplementation: case series and literature review.
Review in Internal and emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review.Nutrients · 2019Pooled it
- Synergistic Anti-Obesity Effect ofFood science & nutrition · 2026Article
- Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements usingFEBS open bio · 2026Article
- Therapeutic Antitoxoplasmosis Potential ofJournal of tropical medicine · 2026Article
- Hepatotoxicity of dietary supplements containingPharmaceutical biology · 2025Review
- Article
- Association between weight loss agents and elevated liver enzymes: a population-based cross-sectional study.Scientific reports · 2023Article
- Interaction ofAntioxidants (Basel, Switzerland) · 2023Article
- Recent advancements in pharmacological strategies to modulate energy balance for combating obesity.RSC medicinal chemistry · 2023Review
- Weight Loss Supplements.Molecules (Basel, Switzerland) · 2023Review
- Article
- Recent Advances inACS omega · 2022Review
- Article
- Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Article
- Pharmacological Activity ofPharmaceuticals (Basel, Switzerland) · 2021Review
- Urantide prevents CCl4‑induced acute liver injury in rats by regulating the MAPK signalling pathway.Molecular medicine reports · 2021Article
- Dietary Supplements-For Whom? The Current State of Knowledge about the Health Effects of Selected Supplement Use.International journal of environmental research and public health · 2021Review
- Herb-induced liver injury: Systematic review and meta-analysis.World journal of clinical cases · 2021Article
- Risks Associated with the Use of Garcinia as a Nutritional Complement to Lose Weight.Nutrients · 2021Review
- Medicinal Potential ofMolecules (Basel, Switzerland) · 2020Review
Corrections and comments
- Commented on by
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herbal weight-loss supplements are sold as self-medication products, and are often used under the misconception that their natural origin guarantees their safety. Food supplements are not required to provide any benefit/risk profile evaluation before marketing; however, possible risks associated with use of herbal extracts in food supplements are becoming more and more documented in the literature. Some herbs are listed as the leading cause of herb-induced liver injury, with a severe or potentially lethal clinical course, and unpredictable herb-drug interactions. Garcinia cambogia (GC) extract and GC-containing products are some of the most popular dietary supplements currently marketed for weight loss. Here, we present four cases of acute liver failure in women taking GC extract for weight loss, and a literature review of clinical evidences about hepatic toxicity in patients taking dietary supplements containing GC extract.
Indexed as
Identifiers
29802521What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.