Evidence map›Paper›PMID 29802415›Full record

ArticleInternational journal of public health2018

Cardiovascular disease prevention at the workplace: assessing the prognostic value of lifestyle risk factors and job-related conditions.

Giovanni Veronesi, Rossana Borchini, Paul Landsbergis, Licia Iacoviello, Francesco Gianfagna, Patrick Tayoun, Guido Grassi, Giancarlo Cesana, Marco Mario Ferrario, Cohorts Collaborative Study in Northern Italy (CCSNI) Research Group

Abstract read
In one paragraph

Article in International journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Effect of Periodontitis and Toothbrushing Frequency on Obesity Onset: A Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giovanni VeronesiDepartment of Medicine and Surgery, Research Centre in Epidemiology and Preventive Medicine, University of Insubria, Varese, Italy. giovanni.veronesi@uninsubria.it.
Rossana BorchiniOccupational Medicine Unit, Varese Hospital and University of Insubria, Varese, Italy.
Paul LandsbergisDepartment of Environmental and Occupational Health Sciences, SUNY Downstate Medical Center, New York, USA.
Licia IacovielloDepartment of Medicine and Surgery, Research Centre in Epidemiology and Preventive Medicine, University of Insubria, Varese, Italy.
Francesco GianfagnaDepartment of Medicine and Surgery, Research Centre in Epidemiology and Preventive Medicine, University of Insubria, Varese, Italy.
Patrick TayounSchool of Medicine, University of Insubria, Varese, Italy.
Guido GrassiClinica Medica, University of Milano-Bicocca, Monza, Italy.
Giancarlo CesanaResearch Centre on Public Health, Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.
Marco Mario FerrarioDepartment of Medicine and Surgery, Research Centre in Epidemiology and Preventive Medicine, University of Insubria, Varese, Italy.
Cohorts Collaborative Study in Northern Italy (CCSNI) Research Group

Funding

Health Administration of the Lombardia Region 10800/2009Health Administration of the Lombardia Region 17155/2004Italian Ministry of Health 2012/597
6 · The paper itself

Abstract

objectivesThe prognostic utility of lifestyle risk factors and job-related conditions (LS&JRC) for cardiovascular disease (CVD) risk stratification remains to be clarified.

methodsWe investigated discrimination and clinical utility of LS&JRC among 2532 workers, 35-64 years old, CVD-free at the time of recruitment (1989-1996) in four prospective cohorts in Northern Italy, and followed up (median 14 years) until first major coronary event or ischemic stroke, fatal or non-fatal. From a Cox model including cigarette smoking, alcohol intake, occupational and sport physical activity and job strain, we estimated 10-year discrimination as the area under the ROC curve (AUC), and clinical utility as the Net Benefit.

resultsN = 162 events occurred during follow-up (10-year risk: 4.3%). The LS&JRC model showed the same discrimination (AUC = 0.753, 95% CI 0.700-0.780) as blood lipids, blood pressure, smoking and diabetes (AUC = 0.753), consistently across occupational classes. Among workers at low CVD risk (n = 1832, 91 CVD events), 687 were at increased LS&JRC risk; of these, 1 every 15 was a case, resulting in a positive Net Benefit (1.27; 95% CI 0.68-2.16).

conclusionsLS&JRC are as accurate as clinical risk factors in identifying future cardiovascular events among working males. Our results support initiatives to improve total health at work as strategies to prevent cardiovascular disease.

Indexed as

Occupational HealthAdultCardiovascular DiseasesEmploymentFemaleHumansItalyLife StyleMaleMiddle AgedPrognosisProspective StudiesRisk FactorsCardiovascular preventionClinical utilityDiscriminationGlobal workers’ healthJob strainLifestyleRisk estimationWorkplace

Identifiers

PMID29802415
PMCPMC6015612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.