Evidence map›Paper›PMID 29802306›Full record

ArticleScientific reports2018

Effects of thermal treatment on the adhesion strength and osteoinductive activity of single-layer graphene sheets on titanium substrates.

Ming Gu, Longwei Lv, Feng Du, Tianxiao Niu, Tong Chen, Dandan Xia, Siyi Wang, Xiao Zhao, Jianzhang Liu, Yunsong Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
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  7. [Progress in antibacterial/osteogenesis dual-functional surface modification strategy of titanium-based implants].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Review
  8. Review
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  11. Article
  12. Graphene for Antimicrobial and Coating Application.International journal of molecular sciences · 2022
    Review
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  16. Review
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  18. Article
  19. Graphene-Reinforced Titanium Enhances Soft Tissue Seal.Frontiers in bioengineering and biotechnology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ming GuDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Longwei LvDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Feng DuDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, 100871, PR China.
Tianxiao NiuDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, 100871, PR China.
Tong ChenDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Dandan XiaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Siyi WangDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Xiao ZhaoDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Jianzhang LiuDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Yunsong LiuDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China. kqliuyunsong@163.com.ORCID 0000-0001-8364-1898
Chunyang XiongDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, 100871, PR China.
Yongsheng ZhouDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Beijing, 100081, PR China.
Peking University · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, dental implants have become the preferred approach for the restoration of missing teeth. At present, most dental implants are made of pure titanium, and are affected by peri-implantitis and bone resorption, which usually start from the implant neck, due to the complex environment in this region. To address these issues, in this study we modified the surface of titanium (Ti) implants to exploit the antibacterial and osteoinductive effects of single-layer graphene sheets. Chemical vapor deposition (CVD)-grown single-layer graphene sheets were transferred to titanium discs, and a method for improving the adhesion strength of graphene on Ti was developed due to compromised adhesion strength between graphene and titanium surface. A thermal treatment of 2 h at 160 °C was found to enhance the adhesion strength of graphene on Ti to facilitate clinical transformation. Graphene coatings of Ti enhanced cell adhesion and osteogenic differentiation, and imparted antibacterial activity to Ti substrate; these favorable effects were not affected by the thermal treatment. In summary, the present study elucidated the effects of a thermal treatment on the adhesion strength and osteoinductive activity of single-layer graphene sheets on titanium substrates.

Identifiers

PMID29802306
PMCPMC5970187
OpenAlexW2806563899

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.