Evidence map›Paper›PMID 29802295›Full record

ArticleNature communications2018

Identification of a unique Ca

Zhicheng Zuo, Rachel N Smith, Zhenglan Chen, Amruta S Agharkar, Heather D Snell, Renqi Huang, Jin Liu, Eric B Gonzales

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

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  12. Review
  13. Citric Acid in Drug Formulations Causes Pain by Potentiating Acid-Sensing Ion Channel 1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
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  15. Review
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  17. A NaThe Journal of biological chemistry · 2019
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhicheng ZuoDepartment of Pharmaceutical Sciences, University of North Texas System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Rachel N SmithDepartment of Pharmacology & Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Zhenglan ChenDepartment of Pharmacology & Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Amruta S AgharkarDepartment of Pharmacology & Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Heather D SnellDepartment of Pharmacology & Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Renqi HuangDepartment of Pharmacology & Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Jin LiuDepartment of Pharmaceutical Sciences, University of North Texas System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA. jin.liu@unthsc.edu.
Eric B GonzalesDepartment of Medical Education, TCU and UNTHSC School of Medicine (Candidate for LCME accreditation), Fort Worth, TX, 76129, USA. ericb.gonzales@fwmdschool.org.
University of North Texas Health Science Center · USUniversity of North Texas System · USUniversity of North Texas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid-sensing ion channels (ASICs) evolved to sense changes in extracellular acidity with the divalent cation calcium (Ca

Indexed as

Acid Sensing Ion ChannelsAnimalsBinding SitesCalciumCations, DivalentCHO CellsCricetulusGlutamic AcidGlycineIon Channel GatingMolecular Dynamics SimulationMutagenesis, Site-DirectedProtein DomainsStructure-Activity RelationshipAcid Sensing Ion ChannelsASIC3 protein, ratCalciumCations, DivalentGlutamic AcidGlycine

Identifiers

PMID29802295
PMCPMC5970173
OpenAlexW2804460103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.