Evidence map›Paper›PMID 29802153›Full record

ArticleCold Spring Harbor molecular case studies2018

Co-occurrence of a maternally inherited

Katarzyna Polonis, Patrick R Blackburn, Raul A Urrutia, Gwen A Lomberk, Teresa Kruisselbrink, Margot A Cousin, Nicole J Boczek, Nicole L Hoppman, Dusica Babovic-Vuksanovic, Eric W Klee and 1 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. PRC2 functions in development and congenital disorders.Development (Cambridge, England) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Katarzyna Polonis *Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Patrick R Blackburn *Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Raul A UrrutiaLaboratory of Epigenetics and Chromatin Dynamics, Epigenomics Translational Program, Mayo Clinic, Rochester, Minnesota 55905, USA.
Gwen A LomberkLaboratory of Epigenetics and Chromatin Dynamics, Epigenomics Translational Program, Mayo Clinic, Rochester, Minnesota 55905, USA.
Teresa KruisselbrinkCenter for Individualized Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Margot A CousinDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.
Nicole J BoczekDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Nicole L HoppmanDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Dusica Babovic-VuksanovicCenter for Individualized Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Eric W KleeDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Pavel N PichurinCenter for Individualized Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Mayo Clinic · USMayo Clinic in Florida · USMedical College of Wisconsin · US

Funding

ZINC FINGER GENES AND PANCREATIC CELL GROWTHR01DK052913 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI LOMBERK, GWEN, URRUTIA, RAUL A. · 1998 to 2023
$7.0M
NIDDK NIH HHS R01 DK052913
6 · The paper itself

Abstract

Overgrowth syndromes are a clinically heterogeneous group of disorders characterized by localized or generalized tissue overgrowth and varying degrees of developmental and intellectual disability. An expanding list of genes associated with overgrowth syndromes include the histone methyltransferase genes

Indexed as

Gene DuplicationAbnormalities, MultipleAdultChildCongenital HypothyroidismCraniofacial AbnormalitiesDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AEnhancer of Zeste Homolog 2 ProteinFemaleGene DosageHand Deformities, CongenitalHumansMalePedigreePhenotypeDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanbilateral talipes equinovarusdelayed gross motor developmentgeneralized neonatal hypotoniahip dysplasiamicroretrognathiamoderate expressive language delaymoderate global developmental delaymoderate intrauterine growth retardationneuroblastomaovergrowthshort stature

Identifiers

PMID29802153
PMCPMC6071565
OpenAlexW2804286394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.