Evidence map›Paper›PMID 29802127›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Human Naive T Cells Express Functional CXCL8 and Promote Tumorigenesis.

Joel Crespo, Ke Wu, Wei Li, Ilona Kryczek, Tomasz Maj, Linda Vatan, Shuang Wei, Anthony W Opipari, Weiping Zou

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Microbial cell (Graz, Austria) · 2025
    Article
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  8. High-throughput single-сell sequencing in cancer research.Signal transduction and targeted therapy · 2022
    Review
  9. Article
  10. Article
  11. Frontiers in cellular and infection microbiology · 2021
    Article
  12. Article
  13. The clinical implication of CD45RACancer medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Joel CrespoDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.
Ke WuDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.ORCID 0000-0002-5610-2714
Wei LiDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.
Ilona KryczekDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.ORCID 0000-0002-3130-2533
Tomasz MajDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.
Linda VatanDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.
Shuang WeiDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109.ORCID 0000-0002-2703-5268
Anthony W OpipariDepartment of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI 48109.
Weiping ZouDepartment of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109; wzou@umich.edu.
University of Michigan · USUnion Hospital · CN

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THEODORE S LAWRENCE · 1988 to 2026
$178.2M
Naive T cells in Cancer Immune Evasion and ImmunotherapyR01CA217510 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2017 to 2021
$3.3M
Immune Impact on Cancer ChemoresistanceR01CA211016 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2017 to 2021
$3.0M
Immune Regulation in the Microenvironment of Oropharyngeal CancerR01CA171306 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2013 to 2017
$2.8M
Effector T Cell Trafficking in Ovarian CancerR01CA190176 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2015 to 2019
$2.6M
MDSCs in Ovarian CancerR01CA193136 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2015 to 2019
$2.5M
Memory T Cells in the Tumor MicroenvironmentR01CA152470 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2011 to 2015
$1.9M
Human Tregs in Ovarian CancerR01CA099985 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2006 to 2014
$1.8M
Novel immunosupressive macrophages in human ovarian tumorR01CA123088 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2007 to 2011
$1.4M
NCI NIH HHS P30 CA046592NCI NIH HHS R01 CA099985NCI NIH HHS R01 CA123088NCI NIH HHS R01 CA152470NCI NIH HHS R01 CA171306NCI NIH HHS R01 CA190176NCI NIH HHS R01 CA193136NCI NIH HHS R01 CA211016NCI NIH HHS R01 CA217510
6 · The paper itself

Abstract

Naive T cells are thought to be functionally quiescent. In this study, we studied and compared the phenotype, cytokine profile, and potential function of human naive CD4

Indexed as

AnimalsBlood CellsCarcinogenesisCell Line, TumorCell MovementCytokinesGene Expression RegulationHumansInterleukin-8Lymphocyte ActivationMiceNeoplasms, ExperimentalNeutrophilsPlatelet Endothelial Cell Adhesion Molecule-1T-LymphocytesUmbilical CordCytokinesInterleukin-8Platelet Endothelial Cell Adhesion Molecule-1

Identifiers

PMID29802127
PMCPMC6039239
OpenAlexW2804281796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.