Evidence map›Paper›PMID 29801984›Full record

ArticleInternational journal of hygiene and environmental health2018

Residential distance to major roadways and semen quality, sperm DNA integrity, chromosomal disomy, and serum reproductive hormones among men attending a fertility clinic.

Feiby L Nassan, Jorge E Chavarro, Lidia Mínguez-Alarcón, Paige L Williams, Cigdem Tanrikut, Jennifer B Ford, Ramace Dadd, Melissa J Perry, Russ Hauser, Audrey J Gaskins

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of hygiene and environmental health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Feiby L NassanDepartments of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Departments of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, United States. Electronic address: fen769@mail.harvard.edu.
Jorge E ChavarroDepartments of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Departments of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Channing Division of Network Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, United States.
Lidia Mínguez-AlarcónDepartments of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
Paige L WilliamsDepartments of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Departments of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
Cigdem TanrikutDepartment of Urology, Massachusetts General Hospital, Boston, MA, United States.
Jennifer B FordDepartments of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
Ramace DaddDepartments of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
Melissa J PerryDepartment of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States.
Russ HauserDepartments of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Departments of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Vincent Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Audrey J GaskinsDepartments of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, United States; Channing Division of Network Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, United States.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
PCBs, Phthalates and Male Reproductive HealthR01ES009718 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HAUSER, RUSS B · 1999 to 2018
$11.6M
Maternal Exposure to Air Pollution and Early Pregnancy OutcomesK99ES026648 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI GASKINS, AUDREY JANE · 2017 to 2018
$246k
NIEHS NIH HHS K99 ES026648NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES009718
6 · The paper itself

Abstract

objectiveWe examined associations of residential distance to major roadways, as a proxy for traffic-related air pollution exposures, with sperm characteristics and male reproductive hormones.

designThe cohort included 797 men recruited from Massachusetts General Hospital Fertility Center between 2000 and 2015 to participate in fertility research studies. MATERIALS AND

methodsMen reported their residential addresses at enrollment and provided 1-6 semen samples and a blood sample during follow-up. We estimated the Euclidean distance to major roadways (e.g. interstates and highways: limited access highways, multi-lane highways (not limited access), other numbered routes, and major roads) using information from the Massachusetts Department of Geographic Information Systems. Semen parameters (1238 semen samples), sperm DNA integrity (389 semen samples), chromosomal disomy (101 semen samples), and serum reproductive hormones (405 serum samples) were assessed following standard procedures.

resultsMen in this cohort were primarily Caucasian (86%), not current smokers (92%), with a college or higher education (88%), and had an average age of 36 years and BMI of 27.7 kg/m

conclusionResidential distance to major roadways, as a proxy for traffic-related air pollution exposure, was not related to sperm characteristics or serum reproductive hormones among men attending a fertility clinic in Massachusetts.

Indexed as

Air PollutantsInfertility, MaleSemenSpermatozoaVehicle EmissionsAdultGonadal Steroid HormonesHumansMaleMassachusettsResidence CharacteristicsSemen AnalysisSex Hormone-Binding GlobulinSperm CountAir PollutantsGonadal Steroid HormonesSex Hormone-Binding GlobulinVehicle EmissionsAir pollutionDisomyDNA integrityInfertilityMenProximityReproductive hormoneRoadSemen

Identifiers

PMID29801984
PMCPMC5997566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.