Evidence map›Paper›PMID 29801729›Full record

ArticleSurgery2018

A Cost-Effectiveness Analysis of a Pediatric Operating Room in Uganda.

Ava Yap, Arlene Muzira, Maija Cheung, James Healy, Nasser Kakembo, Phyllis Kisa, David Cunningham, George Youngson, John Sekabira, Reza Yaesoubi and 1 more

Open access · greenAbstract read
In one paragraph

Article in Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Ava YapYale University School of Medicine, New Haven, CT, USA. Electronic address: avacyap@gmail.com.
Arlene MuziraDepartment of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.
Maija CheungDepartment of Surgery, Yale University School of Medicine, New Haven, CT, USA.
James HealyDepartment of Surgery, Yale University School of Medicine, New Haven, CT, USA.
Nasser KakemboDepartment of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.
Phyllis KisaDepartment of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.
David CunninghamThe ARCHIE Foundation, University of Aberdeen, Scotland.
George YoungsonThe ARCHIE Foundation, University of Aberdeen, Scotland.
John SekabiraDepartment of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.
Reza YaesoubiDepartment of Health Management and Policy, Yale School of Public Health, New Haven, CT, USA.
Doruk OzgedizDepartment of Surgery, Yale University School of Medicine, New Haven, CT, USA.
Yale University · USMakerere University · UGMulago Hospital · UGUniversity of Aberdeen · GBYale New Haven Health System · US

Funding

Improving the control of multidrug-resistant tuberculosis through targeted screening and use of novel anti-tuberculosis drugsK01AI119603 · NIAID · YALE UNIVERSITY · PI YAESOUBI, REZA · 2016 to 2019
$518k
NIAID NIH HHS K01 AI119603
6 · The paper itself

Abstract

This study examines the cost-effectiveness of constructing a dedicated pediatric operating room (OR) in Uganda, a country where access to surgical care is limited to 4 pediatric surgeons serving a population of over 20 million children under 15 years of age.

methodsA simulation model using a decision tree template was developed to project the cost and disability-adjusted life-years saved by a pediatric OR in a low-income setting. Parameters are informed by patient outcomes of the surgical procedures performed. Costs of the OR equipment and a literature review were used to calculate the incremental cost-effectiveness ratio of a pediatric OR. One-way and probabilistic sensitivity analysis were performed to assess parameter uncertainty. Economic monetary benefit was calculated using the value of a statistical life approach.

resultsA pediatric OR averted a total of 6,447 disability-adjusted life-years /year (95% uncertainty interval 6,288-6,606) and cost $41,182/year (UI 40,539-41,825) in terms of OR installation. The pediatric operating room had an incremental cost-effectiveness ratio of $6.39 per disability-adjusted life-year averted (95% uncertainty interval of 6.19-6.59), or $397.95 (95% uncertainty interval of 385.41-410.67) per life saved based on the country's average life expectancy in 2015. These values were well within the WHO guidelines of cost-effectiveness threshold. The net economic benefit amounted to $5,336,920 for a year of operation, or $16,371 per patient. The model remained robust with one-way and probabilistic sensitivity analyses.

conclusionThe construction of a pediatric operating room in Uganda is a cost-effective and worthwhile investment, endorsing future decisions to enhance pediatric surgical capacity in the resource-limited settings of Sub-Saharan Africa.

Indexed as

Cost-Benefit AnalysisModels, EconomicSurgical Procedures, OperativeAdolescentChildChild, PreschoolDecision Making, OrganizationalDecision TreesFemaleHealth Services AccessibilityHealth Services Needs and DemandHumansInfantInfant, NewbornLife ExpectancyMale

Identifiers

PMID29801729
PMCPMC6399742
OpenAlexW2803671755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.