Evidence map›Paper›PMID 29801714›Full record

ArticleSexual medicine2018

Deep Dyspareunia and Sexual Quality of Life in Women With Endometriosis.

Leona K Shum, Mohamed A Bedaiwy, Catherine Allaire, Christina Williams, Heather Noga, Arianne Albert, Sarka Lisonkova, Paul J Yong

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sexual medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02911090 enrolling by invitationnot on this map

Endometriosis Pelvic Pain Interdisciplinary Cohort (EPPIC) Data Registry

Typeobservational_patient_registrySponsorBC Women's Hospital & Health CentreRan2016 to 2028Enrolled5,000ConditionsEndometriosisArmsData Registry
NCT07245537 completednot on this mapstarted 2024, after this paper: background citation

EndoGym Progetto di Riabilitazione Del Pavimento Pelvico e Trattamento Del Dolore Miofasciale e Dispareunia Tramite la Pratica Dello Yoga in Pazienti Con Diagnosi di Endometriosi.

Typeobservational_patient_registrySponsorAzienda Ospedaliero-Universitaria di ModenaRan2024 to 2025Enrolled82ConditionsEndometriosisArmsYoga, Pelvic Floor Physiotherapy
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Leona K ShumSchool of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Mohamed A BedaiwyDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada; BC Women's Center for Pelvic Pain and Endometriosis, Vancouver, BC, Canada; Women's Health Research Institute, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada.
Catherine AllaireDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada; BC Women's Center for Pelvic Pain and Endometriosis, Vancouver, BC, Canada.
Christina WilliamsDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada; BC Women's Center for Pelvic Pain and Endometriosis, Vancouver, BC, Canada.
Heather NogaWomen's Health Research Institute, Vancouver, BC, Canada.
Arianne AlbertDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada; Women's Health Research Institute, Vancouver, BC, Canada.
Sarka LisonkovaDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada.
Paul J YongDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada; BC Women's Center for Pelvic Pain and Endometriosis, Vancouver, BC, Canada; Women's Health Research Institute, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada. Electronic address: paul.yong@vch.ca.
University of British Columbia · CASpinal Cord Injury BC · CABC Children's Hospital · CABritish Columbia Centre of Excellence for Women's Health · CAWomen's Health Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDeep dyspareunia occurs in half of women with endometriosis, a condition present in 10% of reproductive-age women and associated with negative effects on sexual quality of life (SQoL). However, women with endometriosis can have other clinical factors (eg, superficial dyspareunia, other pelvic pains, and psychological or pain conditions) possibly affecting SQoL.

aimsTo determine whether deep dyspareunia is associated with SQoL in women with endometriosis, independent of potential confounders.

methodsThis study involved a prospective patient registry of women at a tertiary-level referral center for endometriosis and pelvic pain. Inclusion criteria were (i) referrals to the center recruited into the registry from January 2014 through December 2016 and (ii) subsequent surgery at the center with histologic confirmation of endometriosis. Exclusion criteria included menopausal status, age at least 50 years, never sexually active, or did not answer dyspareunia or SQoL questions. Bi-variable tests and multiple linear regression analysis were performed.

main outcome measuresSQoL measured by the 5-item sexual intercourse subscale of the Endometriosis Health Profile-30 (EHP-30) modular questionnaire (0-100%, with higher scores indicating worse SQoL).

resultsConsent rate for the prospective registry was 87%; 277 women met the study criteria (mean age = 34.2 ± 7.1 years). Most women had stage I to II endometriosis at time of surgery (64%), with the remaining having stage III to IV endometriosis. Through regression analysis, worse SQoL (higher EHP-30 sexual intercourse subscale score) was independently associated with: more severe deep dyspareunia (P < .0001), more severe superficial dyspareunia (P < .0001), increased depression (P < .001), higher pain catastrophizing (P = .04), bladder pain syndrome (P = .02), heterosexual orientation (P < .001), and new referral status (P = .02).

conclusionIn women with endometriosis at a tertiary referral center, more severe deep dyspareunia was associated with worse SQoL, independent of superficial dyspareunia, psychological comorbidities, and other potential confounders. Shum LK, Bedaiwy MA, Allaire C, et al. Deep Dyspareunia and Sexual Quality of Life in Women With Endometriosis. Sex Med 2018;6:224-233.

Indexed as

Deep DyspareuniaEndometriosisSexual Quality of LifeSuperficial Dyspareunia

Identifiers

PMID29801714
PMCPMC6085224
OpenAlexW2804694796

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.