ArticleJournal of epidemiology and global health2018
Distribution of hemoglobinopathy disorders in Saudi Arabia based on data from the premarital screening and genetic counseling program, 2011-2015.
Article in Journal of epidemiology and global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
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Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review.BioMed research international · 2020Pooled it
- CT Features of Sickle Cell Disease-Associated Pulmonary Hypertension.Journal of clinical medicine · 2026Article
- Distribution of Abnormal Hemoglobins in Saudi Arabia: Analysis of Private Sector Laboratory Data.Journal of epidemiology and global health · 2026Article
- Frequency of Alloimmunization in Patients on Regular Blood Transfusion in Riyadh, Saudi Arabia: A Multicenter Retrospective Study.Journal of clinical medicine · 2026Article
- Knowledge, attitudes, and perceptions towards premarital screening among undergraduate university students in Chattogram district, Bangladesh: a cross-sectional study.BMC public health · 2026Article
- Lack of knowledge of thalassemia among non-medical university students in Saudi Arabia: a cross-sectional study.Frontiers in public health · 2026Article
- A Comprehensive Review of Gene Mutations in Inherited Blood Disorders Among the Saudi Population.Human mutation · 2026Review
- Barriers to liver transplantation in the Arab world.World journal of transplantation · 2025Review
- Radiologic Evaluation of Paranasal Sinuses in Sickle Cell Anemia and Thalassemia: Case-Control Study.Laryngoscope investigative otolaryngology · 2025Article
- The Economic Impact of Premarital Screening (PMS) of Sickle Cell Anemia on the Saudi Health System: A Cost Analysis Study.Healthcare (Basel, Switzerland) · 2025Article
- Unmasking iron deficiency and iron deficiency anemia in Saudi Arabia: Data from a large private sector lab.Saudi medical journal · 2025Observational
- Distribution of Hemoglobinopathy Disorders in Al-Kharj Province Based on Data from the Premarital Screening and Genetic Counseling Program.Medicina (Kaunas, Lithuania) · 2025Article
- The direct costs of transfusion-dependent beta-thalassemia in Saudi Arabia: A cost of illness analysis study.Medicine · 2025Article
- The Prevalence and Predictors of Sickle Cell Anemia in the Saudi Arabia General Population: Findings from a Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Awareness and Attitude of the General Population Towards Inherited Hemoglobinopathies in the Premarital Screening Program in the Northern Region of Saudi Arabia.Hematology reports · 2025Article
- Prophylactic vs therapeutic blood transfusions impact on pregnant sickle cell patients.Pakistan journal of medical sciences · 2025Article
- The Distributions of Duffy Antigens and Phenotypes Among Blood Donors in King Abdulaziz Medical City-Western Region, Saudi Arabia: A Cross-Sectional Study.International journal of general medicine · 2025Article
- Nationwide survey on awareness of consanguinity and genetic diseases in Saudi Arabia: challenges and potential solutions to reduce the national healthcare burden.Human genomics · 2024Article
- Outcomes of the premarital screening program in Riyadh Region, KSA in 2021-2022: A cross-sectional study.Journal of Taibah University Medical Sciences · 2024Article
- Prevalence and Regional Distribution of Beta-Hemoglobin Variants in Saudi Arabia: Insights from the National Premarital Screening Program".Journal of epidemiology and global health · 2024Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence rates of β-thalassemia (β-thal) and Sickle Cell Disease (SCD) in Saudi Arabia are considered one of the highest compared to surrounding countries in the Middle East (0.05% and 4.50%, respectively). In this study, Secondary data analysis was obtained from the premarital screening and genetic counseling program (PMSGC), and included 12,30,582 individuals from February 2011 to December 2015. Prevalence rates (per 1000 population) for β-thal and SCD were calculated for carrier status, disease status and their combination. During the 5-year study period, the overall prevalence rate per 1000 population for β-thal was 13.6 (12.9 for the trait and 0.7 for the disease). The prevalence rate for SCD was 49.6 (45.8 for the trait and 3.8 for the disease). Rates for β-thal were found to decrease from 24.2 in 2011, to 12 in 2015. However, SCD rates remained rather constant and ranged from 42.3 in 2011 to 49.8 in 2015. The highest rate for both β-thal and SCD was observed in the Eastern and Southern regions. This result reflects major accomplishment of the PMSGC. This study recommends further improvement in preventive measures in high-risk regions, and enhanced community awareness to provide the highest rate reduction for these disorders.
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