ArticleAsian Pacific journal of cancer prevention : APJCP2018
Association between Dietary Inflammatory Index (DII) and Risk of Breast Cancer: a Case-Control Study
Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Associations Between Dietary Factors and Breast Cancer Risk: A Systematic Review of Evidence from the MENA Region.Nutrients · 2025Pooled it
- Breast cancer risk factors in Iranian women: a systematic review and meta-analysis of matched case-control studies.European journal of medical research · 2022Pooled it
- Dietary inflammatory index and breast cancer risk: an updated meta-analysis of observational studies.European journal of clinical nutrition · 2022Pooled it
- Pooled it
- Dietary inflammatory index and risk of gynecological cancers: a systematic review and meta-analysis of observational studies.Journal of gynecologic oncology · 2019Pooled it
- How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in GermlineNutrients · 2023Trial
- The association between the Dietary Inflammatory Index and breast cancer risk: an updated systematic review and meta-analysis.Frontiers in nutrition · 2026Review
- Combined association between dietary inflammatory index-related dietary patterns and physical activity with frailty in Chinese older adults: findings from a cross-sectional.Frontiers in public health · 2025Article
- Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review.Nutrients · 2024Article
- Fasting mimicking diet during neo-adjuvant chemotherapy in breast cancer patients: a randomized controlled trial study.Frontiers in nutrition · 2024Article
- Nutritional Metabolomics in Diet-Breast Cancer Relations: Current Research, Challenges, and Future Directions-A Review.Biomedicines · 2023Review
- Dietary inflammatory index and odds of breast cancer: A case-control study.Food science & nutrition · 2021Article
- A case-control study in France showing that a pro-inflammatory diet is associated with a higher risk of breast cancer.Scientific reports · 2021Article
- Racial differences in dietary choices and their relationship to inflammatory potential in childbearing age women at risk for exposure to COVID-19.Nutrition research (New York, N.Y.) · 2021Article
- The association between food diversity and serum antioxidant indices in cataract patients compared to healthy subjects.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- A pro-inflammatory diet increases the likelihood of obesity and overweight in adolescent boys: a case-control study.Diabetology & metabolic syndrome · 2020Article
- Higher Dietary Inflammatory Index Scores are Associated with Increased Odds of Benign Breast Diseases in a Case-Control Study.Journal of inflammation research · 2020Article
- The Association between Dietary Inflammatory Index (DII) and Cancer Risk in Korea: A Prospective Cohort Study within the KoGES-HEXA Study.Nutrients · 2019Article
- Dietary Inflammatory Index and Risk of Breast Cancer Based on Hormone Receptor Status: A Case-Control Study in Korea.Nutrients · 2019Article
- Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, and Colorectal and Breast Cancer Risk (MCC-Spain Study).Nutrients · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Breast cancer (BrCa) is the most common cancer among women worldwide and is the second leading cause of cancer-related death in women, in developed countries. This cancer is among the top five most common cancers in Iran. Studies have shown that dietary components are implicated in the etiology of BrCa. The existence of molecular connections between inflammation and BrCa has been demonstrated via different bimolecular events. Methods: We examined the ability of the dietary inflammatory index (DIITM) to predict the risk of BrCa. This included 145 cases and 148 controls, who attended the specialized centers. DII scores were computed based on dietary intake assessed using a 168-item FFQ. Logistic regression models were used to estimate multivariable ORs. Results: Modeling DII as a continuous variable in relation to risk of BrCa showed a positive association after adjustment for age and energy (OR=1.76; 95% CI=1.43-2.18); and were nearly identical in the multivariable analyses (OR=1.80; 95% CI=1.42-2.28). DII as tertiles, and adjusting for age and energy, subjects in tertile 3 had an OR of 6.94 (95% CI= 3.26-14.79; P-trend ≤0.0001) in comparison to subjects in tertile 1. After multivariable adjustment, results were essentially identical as in the model adjusting for age and energy (OR tertile 3vs1=7.24; 95% CI=3.14-16.68; P-trend ≤0.001). Sub group analyses revealed similar positive associations with HER 2 receptor +ve, progesterone receptor +ve, estrogen receptor +ve and lymph node invasive cases. Conclusion: Subjects who consumed a more pro-inflammatory diet were at increased risk of BrCa compared to those who consumed a more anti-inflammatory diet.
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